Evidence map›Paper›PMID 40358555›Full record

ArticleAllergy2025

Involvement of IL-13-Induced Dysregulation of BDNF-NTRK2 Pathway in Symptoms of Eosinophilic Esophagitis.

Kasumi Osonoi, Akinari Sawada, Yuki Maekawa, Mari Yamaguchi, Shingo Yamada, Kazuhiro Matsuyama, Mark Rochman, Marc E Rothenberg, Xiaobo Han, Naoki Matsuda and 4 more

Abstract readLetter
In one paragraph

Article in Allergy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Kasumi OsonoiDivision of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Akinari SawadaDepartment of Gastroenterology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Yuki MaekawaDivision of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Mari YamaguchiDivision of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Shingo YamadaDivision of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.ORCID https://orcid.org/0000-0001-9250-6241
Kazuhiro MatsuyamaDivision of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Mark RochmanDivision of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Marc E RothenbergDivision of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Xiaobo HanDepartment of Electronics, Graduate School of Engineering, Tohoku Institute of Technology, Sendai, Miyagi, Japan.
Naoki MatsudaDepartment of Electronics, Graduate School of Engineering, Tohoku Institute of Technology, Sendai, Miyagi, Japan.
Ikuro SuzukiDepartment of Electronics, Graduate School of Engineering, Tohoku Institute of Technology, Sendai, Miyagi, Japan.
Fumio TanakaDepartment of Gastroenterology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Yasuhiro FujiwaraDepartment of Gastroenterology, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Tetsuo ShodaDivision of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.ORCID https://orcid.org/0000-0001-8337-5438

Funding

Stem Cell/Organoid and Genome Editing CoreP30DK078392 · NIDDK · CINCINNATI CHILDRENS HOSP MED CTR · PI Alexander Miethke · 2007 to 2026
$24.4M
Combinatory Effects of Genetic Variants in Eosinophilic EsophagitisR00AI158660 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI SHODA, TETSUO · 2023 to 2024
$498k
NIAID NIH HHS R00 AI158660NIDDK NIH HHS P30 DK078392NIH HHS
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

asymptomatic esophageal eosinophiliabrain‐derived neurotrophic factorEoE diagnostic paneleosinophilic esophagitisIL‐13iPSC‐derived sensory neuronsneuropathic and inflammatory pain panelneurotrophic receptor tyrosine kinase 2

Identifiers

PMID40358555
PMCPMC12311799

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.