Evidence map›Paper›PMID 40358458›Full record

ReviewChemical communications (Cambridge, England)2025

Isothermal assembly of DNA nanostructures.

Arun Richard Chandrasekaran

Abstract readReview
In one paragraph

Review in Chemical communications (Cambridge, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Arun Richard ChandrasekaranThe RNA Institute, University at Albany, State University of New York, Albany, NY, USA. arun@albany.edu.ORCID http://orcid.org/0000-0001-6757-5464

Funding

Programmable DNA Nanostructures as Biomedical and Structural ScaffoldsR35GM150672 · NIGMS · STATE UNIVERSITY OF NEW YORK AT ALBANY · PI Arun Richard Chandrasekaran · 2023 to 2026
$1.7M
NIGMS NIH HHS R35 GM150672
6 · The paper itself

Abstract

DNA nanostructures are typically assembled using a thermal annealing protocol by heating the DNA mixture to high temperatures and then cooling it down to a lower temperature. Recent efforts have shown the assembly of DNA nanostructures by incubation at constant temperatures in a process called isothermal assembly. DNA motifs, polyhedra, lattices, and other nanostructures based on single-stranded tiles and the DNA origami strategy have all been constructed using the isothermal assembly process. Several additives such as denaturing agents, cationic amino acids, and natural products aid in the isothermal process at room temperature and physiological temperature. This review focusses on the developments in isothermal assembly of DNA nanostructures, key takeaways from recent studies, and the advantages and limitations of isothermal assembly in the broader context of DNA nanotechnology.

Indexed as

DNANanostructuresNanotechnologyTemperatureNucleic Acid ConformationDNA

Identifiers

PMID40358458
PMCPMC12143421

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.