Evidence map›Paper›PMID 40358456›Full record

ArticleAnalytical chemistry2025

Benchmarking of Trapped Ion Mobility Spectrometry in Differentiating Plasmalogens from Other Ether Lipids in Lipidomics Experiments.

Jakob Koch, Lukas Neumann, Katharina Lackner, Monica L Fernández-Quintero, Katrin Watschinger, Markus A Keller

Abstract read
In one paragraph

Article in Analytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jakob KochInstitute of Human Genetics, Medical University of Innsbruck, Innsbruck 6020, Austria.
Lukas NeumannDepartment of Basic Sciences in Engineering Science, University of Innsbruck, Innsbruck 6020, Austria.
Katharina LacknerInstitute of Human Genetics, Medical University of Innsbruck, Innsbruck 6020, Austria.
Monica L Fernández-QuinteroDepartment of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California 92037, United States.ORCID 0000-0002-6811-6283
Katrin WatschingerInstitute of Molecular Biochemistry, Biocenter, Medical University of Innsbruck, Innsbruck 6020, Austria.ORCID 0000-0002-1122-8444
Markus A KellerInstitute of Human Genetics, Medical University of Innsbruck, Innsbruck 6020, Austria.ORCID 0000-0002-8654-9920

Funding

Wellcome Trust
6 · The paper itself

Abstract

Trapped Ion Mobility Spectrometry (TIMS) has demonstrated promising potential as a powerful discriminating method when coupled with mass spectrometry, enhancing the precision of feature annotation. Such a technique is particularly valuable for lipids, where a large number of isobaric but structurally distinct molecular species often coexist within the same sample matrix. In this study, we explored the potential of ion mobility for ether lipid isomer differentiation. Mammalian ether phospholipids are characterized by a fatty alcohol residue at the

Indexed as

EthersIon Mobility SpectrometryLipidomicsLipidsPlasmalogensAnimalsEthersLipidsPlasmalogens

Identifiers

PMID40358456
PMCPMC12120822

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.