Evidence map›Paper›PMID 40358365›Full record

ArticleJournal of proteome research2025

ProteoPlotter: An Executable Proteomics Visualization Tool Compatible with Perseus.

Esther Olabisi-Adeniyi, Jason A McAlister, Daniela Ferretti, Juergen Cox, Jennifer Geddes-McAlister

Abstract read
In one paragraph

Article in Journal of proteome research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Lon protease-mediated secretome profiling inMicrobiology resource announcements · 2026
    Article
  4. Vibe Coding Omics Data Analysis Applications.Journal of proteome research · 2026
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Esther Olabisi-AdeniyiMolecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada.
Jason A McAlisterMolecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada.
Daniela FerrettiMax Planck Institute of Biochemistry, Martinsried 82152, Germany.
Juergen CoxMax Planck Institute of Biochemistry, Martinsried 82152, Germany.ORCID 0000-0001-8597-205X
Jennifer Geddes-McAlisterMolecular and Cellular Biology, University of Guelph, Guelph, Ontario N1G 2W1, Canada.ORCID 0000-0002-4257-2096

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mass spectrometry-based proteomics experiments produce complex data sets requiring robust statistical testing and effective visualization tools to ensure meaningful conclusions are drawn. The publicly available proteomics data analysis platform, Perseus, is extensively used to perform such tasks, but opportunities to enhance visualization tools and promote accessibility of the data exist. In this study, we developed ProteoPlotter, a user-friendly, executable tool to complement Perseus for visualization of proteomics data sets. ProteoPlotter is built on the Shiny framework for R programming and enables illustration of multidimensional proteomics data. ProteoPlotter supports mapping of one-dimensional enrichment analyses, enhanced adaptability of volcano plots through incorporation of Gene Ontology terminology, visualization of 95% confidence intervals in principal component analysis plots using data ellipses, and customizable features. ProteoPlotter is designed for intuitive use by biological and computational researchers alike, providing descriptive instructions (i.e., Help Guide) for preparing and uploading Perseus output files. Herein, we demonstrate the application of ProteoPlotter toward microbial proteome remodeling under altered nutrient conditions and highlight the diversity of visualizations enabled with the platform for enhanced biological insights. Through its comprehensive data visualization capabilities, linked to the power of Perseus data handling and statistical analyses, ProteoPlotter facilitates enhanced visualization of proteomics data to drive new biological discoveries.

Indexed as

ProteomeProteomicsSoftwareMass SpectrometryPrincipal Component AnalysisProteome1D annotation enrichmentdata visualizationdynamic rangeheat mapsKlebsiella pneumoniaePerseusproteomicsUpSet plotsVenn diagramsvolcano plots

Identifiers

PMID40358365
PMCPMC12151067

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.