ArticleThe Journal of infectious diseases2025
Streptococcus pyogenes Surveillance Through Surface Swab Samples to Track the Emergence of Streptococcal Toxic Shock Syndrome in Rural Japan.
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Article in The Journal of infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It carries an expression of concern. Cited by 2 papers.
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2citing papers in PubMed
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Who cites it
2 citing papers in PubMed.
- Genomic epidemiology and molecular characterization ofMicrobiology spectrum · 2026Article
- Development and Validation of a Nomogram for Predicting Multidrug-ResistantInfection and drug resistance · 2025Article
Corrections and comments
- Expression of concern
Authors and funding
34 authors.
Dhammika Leshan WannigamaDepartment of Infectious Diseases, Faculty of Medicine, Yamagata University and Yamagata University Hospital, Yamagata, Japan.ORCID 0000-0001-6316-1221
Mohan AmarasiriDepartment of Civil and Environmental Engineering, Graduate School of Engineering, Tohoku University, Sendai, Miyagi, Japan.ORCID 0000-0002-3509-3433
Phatthranit PhattharapornjaroenDepartment of Infectious Diseases and Infection Control, Yamagata Prefectural Central Hospital, Yamagata, Japan.ORCID 0000-0002-4391-2929
Cameron HurstDepartment of Infectious Diseases and Infection Control, Yamagata Prefectural Central Hospital, Yamagata, Japan.
Charin ModchangBiophysics Group, Department of Physics, Faculty of Science, Mahidol University, Bangkok, Thailand.ORCID 0000-0002-0739-006X
Yu SuzukiPathogen Hunter's Research Collaborative Team, Department of Infectious Diseases and Infection Control, Yamagata Prefectural Central Hospital, Yamagata, Japan.
Kazunori MoriyaDepartment of Infectious Diseases and Infection Control, Yamagata Prefectural Central Hospital, Yamagata, Japan.
Kazuhiko MiyanagaDivision of Bacteriology, School of Medicine, Jichi Medical University, Tochigi, Japan.
Longzhu CuiDivision of Bacteriology, School of Medicine, Jichi Medical University, Tochigi, Japan.ORCID 0000-0002-8909-3885
Angkana T HuangDepartment of Genetics, University of Cambridge, Cambridge, United Kingdom.
Yoshikazu OkumaPathogen Hunter's Research Collaborative Team, Department of Infectious Diseases and Infection Control, Yamagata Prefectural Central Hospital, Yamagata, Japan.
Daisuke AkaneyaDepartment of Clinical Laboratory, Yamagata Prefectural Central Hospital, Yamagata, Japan.
Junko IgarashiPathogen Hunter's Research Collaborative Team, Department of Infectious Diseases and Infection Control, Yamagata Prefectural Central Hospital, Yamagata, Japan.
Mayu SutoPathogen Hunter's Research Collaborative Team, Department of Infectious Diseases and Infection Control, Yamagata Prefectural Central Hospital, Yamagata, Japan.
Daisuke IshizawaPathogen Hunter's Research Collaborative Team, Department of Infectious Diseases and Infection Control, Yamagata Prefectural Central Hospital, Yamagata, Japan.
Wakana ImamiyaDepartment of Infectious Diseases and Infection Control, Yamagata Prefectural Central Hospital, Yamagata, Japan.
Ayaka IgarashiDepartment of Infectious Diseases and Infection Control, Yamagata Prefectural Central Hospital, Yamagata, Japan.
Yoshitaka ShimotaiDepartment of Infectious Diseases, Faculty of Medicine, Yamagata University and Yamagata University Hospital, Yamagata, Japan.ORCID 0000-0002-9612-3261
Andrew C SingerUK Centre for Ecology and Hydrology, Wallingford, United Kingdom.
Naveen Kumar Devanga RagupathiBiofilms and Antimicrobial Resistance Consortium of Official Development Assistance (ODA) Receiving Countries, The University of Sheffield, Sheffield, United Kingdom.
Takashi FurukawaDepartment of Health Science, Laboratory of Environmental Hygiene, School of Allied Health Sciences/Graduate School of Medical Sciences, Kitasato University, Kanagawa, Japan.
Kazunari SeiDepartment of Health Science, Laboratory of Environmental Hygiene, School of Allied Health Sciences/Graduate School of Medical Sciences, Kitasato University, Kanagawa, Japan.ORCID 0000-0002-0684-6002
Yangzhong WangPathogen Hunter's Research Collaborative Team, Department of Infectious Diseases and Infection Control, Yamagata Prefectural Central Hospital, Yamagata, Japan.
Talerngsak KanjanabuchDivision of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.ORCID 0000-0002-2996-8934
Paul G HigginsFaculty of Medicine and University Hospital Cologne, Institute for Medical Microbiology, Immunology, and Hygiene, University of Cologne, Cologne, Germany.ORCID 0000-0001-8677-9454
Nobuhito NemotoDepartment of Orthopedics, Yamagata Prefectural Central Hospital, Yamagata, Japan.
Aisha KhatibDepartment of Family and Community Medicine, University of Toronto, Toronto, Ontario, Canada.
Anthony KicicWal-Yan Respiratory Research Centre, Telethon Kids Institute, University of Western Australia, Nedlands, Western Australia, Australia.ORCID 0000-0002-0008-9733
Sam TrowsdaleSchool of Environment, University of Auckland, Auckland, New Zealand.ORCID 0000-0001-8907-6885
Parichart HongsingDepartment of Infectious Diseases and Infection Control, Yamagata Prefectural Central Hospital, Yamagata, Japan.
Daisuke SanoDepartment of Civil and Environmental Engineering, Graduate School of Engineering, Tohoku University, Sendai, Miyagi, Japan.ORCID 0000-0001-8075-6972
Kenji ShibuyaTokyo Foundation for Policy Research, Tokyo, Japan.
Shuichi AbeDepartment of Infectious Diseases and Infection Control, Yamagata Prefectural Central Hospital, Yamagata, Japan.ORCID 0000-0001-8138-5077
Hiroshi HamamotoDepartment of Infectious Diseases, Faculty of Medicine, Yamagata University and Yamagata University Hospital, Yamagata, Japan.ORCID 0000-0001-9315-7442
Funding
Balvi Filantropic FundBarry Satz and Ronald Satz Memorial FundCenter of Excellence in Medical BiotechnologyCentre of Excellence in MathematicsJapan Society for the Promotion of Science JP24KF0177MHLW JPMH22HA1007Ministry of Higher Education, Science, Research and Innovation, ThailandRothwell FamilyThailand Center of Excellence in Physics
Abstract
Japan recently experienced a record surge in streptococcal toxic shock syndrome. Our environmental surveillance study reveals that Streptococcus pyogenes persists seasonally, peaking in autumn and winter in rural Japan. The dominant emm1 M1UK sublineage and csrS mutations heighten virulence, highlighting the urgent need for targeted surveillance and interventions.
Indexed as
Shock, SepticStreptococcal InfectionsStreptococcus pyogenesAntigens, BacterialBacterial Outer Membrane ProteinsCarrier ProteinsEpidemiological MonitoringFemaleHumansJapanRural PopulationSeasonsAntigens, BacterialBacterial Outer Membrane ProteinsCarrier Proteinsstreptococcal M proteincsrS mutationsemm1group A Streptococcus (GAS)JapanM1UKnecrotizing fasciitisrural JapanspeBspy1258streptococcal toxic shock syndromeStreptococcus pyogenesSTSS
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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.