Evidence map›Paper›PMID 40358157›Full record

ArticleCells2025

Adaptive Optics-Transscleral Flood Illumination Imaging of Retinal Pigment Epithelium in Dry Age-Related Macular Degeneration.

Laura Kowalczuk, Rémy Dornier, Aurélie Navarro, Fanny Jeunet, Christophe Moser, Francine Behar-Cohen, Irmela Mantel

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Laura KowalczukFaculty of Biology and Medicine, University of Lausanne, Jules-Gonin Eye Hospital, Fondation Asile des Aveugles, 1004 Lausanne, Switzerland.ORCID 0000-0003-0268-9430
Rémy DornierLaboratory of Applied Photonic Devices (LAPD), School of Engineering, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.ORCID 0009-0006-1381-4582
Aurélie NavarroFaculty of Biology and Medicine, University of Lausanne, Jules-Gonin Eye Hospital, Fondation Asile des Aveugles, 1004 Lausanne, Switzerland.
Fanny JeunetFaculty of Biology and Medicine, University of Lausanne, Jules-Gonin Eye Hospital, Fondation Asile des Aveugles, 1004 Lausanne, Switzerland.
Christophe MoserLaboratory of Applied Photonic Devices (LAPD), School of Engineering, École Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
Francine Behar-CohenCentre de Recherche des Cordeliers, UPMC-Paris 6, INSERM U1138, Université Sorbonne Paris Cité, 75006 Paris, France.ORCID 0000-0001-8571-9513
Irmela MantelFaculty of Biology and Medicine, University of Lausanne, Jules-Gonin Eye Hospital, Fondation Asile des Aveugles, 1004 Lausanne, Switzerland.

Funding

European Institute of Innovation and Technology Project ASSESS retinAI phase contrast imaging for Early diagnoSiS_Activity 20694Innosuisse - Swiss Innovation Agency Project 56126.1 IMPULSE- IRIS Imaging Retinal cells In degenerative diSeases
6 · The paper itself

Abstract

Adaptive optics-transscleral flood illumination (AO-TFI) is a novel imaging technique with potential for detecting retinal pigment epithelium (RPE) changes in dry age-related macular degeneration (AMD). This single-center prospective study evaluated its ability to visualize pathological features in AMD. AO-TFI images were acquired using the prototype Cellularis

Indexed as

Geographic AtrophyMacular DegenerationRetinal Pigment EpitheliumAgedAged, 80 and overFemaleHumansMaleMiddle AgedProspective StudiesTomography, Optical Coherenceage-related macular degenerationblood–retinal barriersclinical eye researchhigh-resolution retinal imagingretinal pigment epithelium

Identifiers

PMID40358157
PMCPMC12071642

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.