Evidence map›Paper›PMID 40358088›Full record

ArticleBJPsych open2025

Time trends in life expectancy of people with severe mental illness in Scotland, 2000-2019: population-based study.

Kelly J Fleetwood, Raied Alotaibi, Stine H Scheuer, Daniel J Smith, Sarah H Wild, Caroline A Jackson

Abstract read
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Article in BJPsych open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

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0cells of the map it votes in
6citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kelly J FleetwoodUsher Institute, University of Edinburgh, Edinburgh, UK.ORCID https://orcid.org/0000-0002-1382-3095
Raied AlotaibiUsher Institute, University of Edinburgh, Edinburgh, UK.ORCID https://orcid.org/0000-0002-3505-7002
Stine H ScheuerClinical and Translational Research, Steno Diabetes Centre Copenhagen, Herlev, Denmark.ORCID https://orcid.org/0000-0002-1244-9871
Daniel J SmithCentre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.ORCID https://orcid.org/0000-0002-2267-1951
Sarah H WildUsher Institute, University of Edinburgh, Edinburgh, UK.ORCID https://orcid.org/0000-0001-7824-2569
Caroline A JacksonUsher Institute, University of Edinburgh, Edinburgh, UK.ORCID https://orcid.org/0000-0002-2067-2811

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeople with severe mental illness (SMI) have a higher risk of premature mortality than the general population.

aimsTo investigate whether the life expectancy gap for people with SMI is widening, by determining time trends in excess life-years lost.

methodThis population-based study included people with SMI (schizophrenia, bipolar disorder and major depression) alive on 1 January 2000. We ascertained SMI from psychiatric hospital admission records (1981-2019), and deaths via linkage to the national death register (2000-2019). We used the Life Years Lost (LYL) method to estimate LYL by SMI and sex, compared LYL to the Scottish population and assessed trends over 18 3-year rolling periods.

resultsWe included 28 797 people with schizophrenia, 16 657 with bipolar disorder and 72 504 with major depression. Between 2000 and 2019, life expectancy increased in the Scottish population but the gap widened for people with schizophrenia. For 2000-2002, men and women with schizophrenia lost an excess 9.4 (95% CI 8.5-10.3) and 8.2 (95% CI 7.4-9.0) life-years, respectively, compared with the general population. In 2017-2019, this increased to 11.8 (95% CI 10.9-12.7) and 11.1 (95% CI 10.0-12.1). The life expectancy gap was lower for bipolar disorder and depression and unchanged over time.

conclusionsThe life expectancy gap in people with SMI persisted or widened from 2000 to 2019. Addressing this entrenched disparity requires equitable social, economic and health policies, healthcare re-structure and improved resourcing, and investment in interventions for primary and secondary prevention of SMI and associated comorbidities.

Indexed as

bipolar disorderdepressionlife expectancySchizophrenia

Identifiers

PMID40358088
PMCPMC12089813

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.