Evidence map›Paper›PMID 40358039›Full record

SynthesisPediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology2025

Air pollution and hospitalization risk in infants with bronchiolitis: A systematic review and meta-analysis.

Anna Comotti, Ilaria Alberti, Giulia Carla Immacolata Spolidoro, Emilia Vassilopoulou, Carlo Agostoni, Matteo Bonzini, Michele Carugno, Gregorio Paolo Milani

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Air pollution and hospitalization risk in infants with bronchiolitis: A systematic review and meta-analysis.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. The association between PMAIMS public health · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anna ComottiOccupational Medicine Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Ilaria AlbertiPediatric Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Giulia Carla Immacolata SpolidoroDepartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Emilia VassilopoulouPediatric Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.ORCID https://orcid.org/0000-0002-2665-5908
Carlo AgostoniPediatric Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Matteo BonziniOccupational Medicine Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Michele CarugnoOccupational Medicine Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Gregorio Paolo MilaniPediatric Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.ORCID https://orcid.org/0000-0003-3829-4254

Funding

Ministero della Salute
6 · The paper itself

Abstract

Bronchiolitis is one of the leading causes of hospitalization among infants. Established risk factors include young age, prematurity, and exposure to tobacco smoke. Emerging evidence suggests that air pollution may also contribute to the burden of respiratory diseases. However, its link with bronchiolitis hospitalizations remains debated. To address this, we conducted a systematic review and meta-analysis to assess whether exposure to air pollutants is associated with an increased risk of hospitalization for bronchiolitis in infants. A systematic review and meta-analysis were conducted following the PRISMA guidelines. PubMed, Embase, and Web of Science were searched up to May 2024. Eligible studies examined the relationship between air pollutants and bronchiolitis hospitalizations in infants up to 2 years of age. Meta-analyses were performed to estimate the association between pollutant levels and hospitalization risk. Out of 788 identified studies, 23 met the inclusion criteria. Studies were heterogeneous regarding design, adjustment for confounders, and statistical approaches. Particulate matter with diameter ≤2.5 μm (PM

Indexed as

Air PollutantsAir PollutionBronchiolitisEnvironmental ExposureHospitalizationHumansInfantInfant, NewbornParticulate MatterRisk FactorsAir PollutantsParticulate Matterair pollutionbronchiolitishospitalizationinfantssystematic review

Identifiers

PMID40358039
PMCPMC12070665

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.