Evidence map›Paper›PMID 40357921›Full record

ArticlePsychological medicine2025

A counterweight model for understanding and treating persecutory delusions.

Daniel Freeman, Louise Isham, Felicity Waite

Abstract readEditorial
In one paragraph

Article in Psychological medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Article
  3. An excitement building in the development of psychological treatments for schizophrenia.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Daniel FreemanDepartment of Experimental Psychology, University of Oxford, Oxford, UK.ORCID 0000-0002-2541-2197
Louise IshamDepartment of Experimental Psychology, University of Oxford, Oxford, UK.
Felicity WaiteDepartment of Experimental Psychology, University of Oxford, Oxford, UK.

Funding

Wellcome 102176/B/13/ZWellcome Trust
6 · The paper itself

Abstract

Direct challenge seldom leads to change in strongly held beliefs such as persecutory delusions. A better route is to develop an alternative belief that can coexist with the delusion. The best such beliefs function as counterweights to the delusion. Over time, the scales shift. The alternative belief becomes more powerful than the delusion. In this paper, we set out such a model of persecutory delusions (or severe paranoia) and describe how it inherently translates theoretical understanding into treatment routes. Severe paranoia occurs when the adaptive cognitive processes of deciding whether to trust become overly weighted to mistrust. An inaccurate threat belief is formed, and the person feels very unsafe. Hence, overcoming the delusion means developing a counterweighting belief. It means building the alternative view that the world is safe enough for the person now and going forward. This, in turn, is done by

Indexed as

DelusionsModels, PsychologicalParanoid DisordersHumansCognitiveDelusionsParanoiaPersecutoryPsychosisSchizophreniaTreatment

Identifiers

PMID40357921
PMCPMC12094649

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.