Evidence map›Paper›PMID 40357917›Full record

SynthesisPsychological medicine2025

Brief psychological interventions for schizophrenia: a systematic review and meta-analysis.

Blue Pike, Leire Ambrosio, Lyn Ellett

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Psychological medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Blue PikeRecovery Service, Hampshire and Isle of Wight Healthcare NHS Foundation Trust, Isle of Wight, UK.ORCID 0009-0001-9453-4788
Leire AmbrosioSchool of Health and Life Sciences, University of Southampton, Southampton, UK.ORCID 0000-0002-9450-7210
Lyn EllettSchool of Psychology, University of Southampton, Southampton, UK.ORCID 0000-0002-6051-3604

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough cognitive behavioral therapy for people diagnosed with schizophrenia (CBTp) is recommended in clinical guidelines internationally, rates of implementation are low. One consequence of this has been the development of brief individual psychological interventions, which are shorter than the recommended minimum of 16 sessions for CBTp. This article is the first to systematically identify the brief interventions that exist for people diagnosed with schizophrenia and to determine their effectiveness using meta-analysis.

methodsFive electronic databases (PsycINFO, MEDLINE, CINAHL, EMBASE, and Web of Science) were searched for peer-reviewed randomized controlled trials or experimental studies of brief individual psychological interventions delivered in community settings. Random effects meta-analysis was used to integrate effect sizes, due to the heterogeneity of included studies.

resultsFourteen studies were identified (n = 1,382) that measured thirty clinical outcomes and included six intervention types - brief CBT, memory training, digital motivation support, reasoning training, psychoeducation, and virtual reality. Collectively, brief psychological interventions were found to be effective for psychotic symptoms (SMD -0.285, p < 0.01), paranoia (SMD -0.277, p < 0.05), data gathering (SMD 0.38, p < 0.01), depression (SMD -0.906, p < 0.05) and wellbeing (SMD 0.405, p < 0.01). For intervention types, brief CBT was effective for psychotic symptoms (SMD -0.32, p < .001), and reasoning training was effective for data gathering (SMD 0.38, p < 0.01).

conclusionsOverall, the evidence suggests that brief psychological interventions are effective for several key difficulties associated with schizophrenia, providing an opportunity to improve both access to, and choice of, treatment for individuals diagnosed with schizophrenia.

Indexed as

Cognitive Behavioral TherapyPsychotherapy, BriefSchizophreniaHumansbrief interventionCBTmeta-analysisschizophreniasystematic review

Identifiers

PMID40357917
PMCPMC12094642

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.