Evidence map›Paper›PMID 40357895›Full record

ArticleClinical cardiology2025

Clinical Characteristics and Outcomes of Catheter Ablation in Young Patients With Atrial Fibrillation.

Xuewen Wang, Qiqi Cao, Tao Liu, Fan Zhang, Shujuan Zhang, Shaobo Shi, Qingyan Zhao, He Huang, Congxin Huang

Abstract readMulticenter Study
In one paragraph

Article in Clinical cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xuewen WangCardiovascular Department, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Qiqi CaoCardiovascular Department, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Tao LiuCardiovascular Department, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Fan ZhangCardiovascular Department, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Shujuan ZhangCardiovascular Department, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Shaobo ShiCardiovascular Department, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Qingyan ZhaoCardiovascular Department, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.ORCID http://orcid.org/0000-0002-9610-2452
He HuangCardiovascular Department, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.ORCID http://orcid.org/0000-0003-3915-2733
Congxin HuangCardiovascular Department, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.

Funding

The study was supported by the Interdisciplinary Innovative Talents Foundation from Renmin Hospital of Wuhan University (JCRCZN-2022-003) and the Fundamental Research Funds for the Central Universities.
6 · The paper itself

Abstract

backgroundData concerning young patients with atrial fibrillation (AF) are currently limited. HYPOTHESIS: This study aimed to assess the clinical characteristics and risk factors for AF recurrence in young patients following catheter ablation (CA).

methodsAll AF patients aged ≤ 45 years who underwent CA were identified from the China Atrial Fibrillation Center database between September 2018 and September 2023. Baseline clinical characteristics, procedural details, and follow-up outcomes were compared between the paroxysmal and non-paroxysmal cohorts.

resultsA total of 6,531 young patients with AF were included in the final analysis, with an average age of 37.7 ± 5.5 years, 77.1% were male, and 65.2% with paroxysmal AF. The primary comorbidities were hypertension (16.2%), heart failure (8.4%), valvular heart disease (3.5%), diabetes mellitus (3.2%), peripheral arterial disease (2.8%), stroke/transient ischemic attack (2.5%), and cardiomyopathy (2.2%). Following CA, the recurrence rate of AF post-CA was 14.4% across the entire cohort, with a lower recurrence rate in the paroxysmal AF group compared to the non-paroxysmal AF group (10.6% vs. 19.7%, p < 0.001). Non-paroxysmal AF (HR 2.34, 95% CI 1.62 to 3.36, p < 0.001) and hypertension (HR 1.69, 95% CI 1.09 to 2.63, p = 0.019) were identified as independent predictors for AF recurrence.

conclusionYoung AF patients who undergo CA exhibit a low recurrence rate and a notable improvement in symptoms post-CA. Non-paroxysmal AF and hypertension emerge as primary contributors to AF recurrence following CA in this population.

Indexed as

Atrial FibrillationCatheter AblationAdultAge FactorsChinaFemaleFollow-Up StudiesHumansMaleMiddle AgedRecurrenceRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment Outcomeatrial fibrillationcatheter ablationclinical characteristicyoung people

Identifiers

PMID40357895
PMCPMC12070253

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