ArticleJournal of the American Heart Association2025
Clinical and Phenotypic Correlates of Mitral Valve Prolapse in Marfan Syndrome: The Cornell Aortic Aneurysm Registry.
Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Outcomes of Type B Dissection in Marfan Syndrome: The Cornell Aortic Aneurysm Registry.Journal of the American Heart Association · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundMitral valve prolapse (MVP) is highly prevalent in Marfan syndrome (MFS), but its associations with significant valvular regurgitation, the need for mitral valve (MV) surgery or elective aortic root replacement, and the occurrence of aortic dissection in MFS are not fully elucidated.
methodsImaging, anthropometric, cardiovascular disease, and surgical data were compared in patients with and without MVP in a large, single-center MFS registry.
resultsOf 352 patients with MFS, MVP was present in 237 (67.3%) and was more common in women (73.3% versus 59.9%,
conclusionsMVP is highly prevalent in MFS and more likely to necessitate MV surgery compared with the general population, particularly among women. The associations of MV surgery with aortic root replacement and type B dissection indicate that MVP associated with the need for mitral surgery tracks with a more severe aortic phenotype in MFS.
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