ArticleFrontiers in psychiatry2025
Development and validation of a postoperative delirium risk prediction model for non-cardiac surgery in elderly patients.
Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Effect of Liposomal Bupivacaine for Fascia Iliaca Compartment Block on Early Postoperative Recovery Quality in Elderly Patients Undergoing Total Hip Arthroplasty: A Retrospective Cohort Study.Drug design, development and therapy · 2026Article
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10 authors.
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Abstract
Background: Postoperative delirium (POD) is one of the common central nervous system complications in elderly patients after non-cardiac surgery. Therefore, it is necessary to develop and validate a preoperative model for POD risk prediction. Methods: This study selected 663 elderly patients undergoing non-cardiac elective surgery under general anesthesia for tracheal intubation in general surgery, from September 1 Results: A total of 663 elderly patients were enrolled in this study, and 131 (19.76%) patients developed POD. The incidence of POD in each department was not statistically significant. The predictors in the POD column line graph included age, Mini Mental State Examination (MMSE) score, history of diabetes, years of education, sleep quality index, ASA classification, duration of anesthesia and NRS score. The formula Z= 8.293 + 0.102 × age - 1.214 × MMSE + 1.285 × diabetesHistory - 0.304 × yearsOfEducation + 0.602 × PSQI + 1.893 × ASA + 0.027 × anesthesiaTime + 1.297 × NRS. Conducive to the validation group to evaluate the prediction model, the validation group AUC is 0.939 (95% CI 0.894-0.969), the sensitivity is 94.44%, and the specificity is 85.09%. The calibration curves show a good fit between the clinically predicted situation and the actual situation. Conclusion: The clinical prediction model constructed based on these independent risk factors has a good predictive performance, which can provide reference for the early screening and prevention of POD in clinical work. Trial registration: ChiCTR2000033639 Retrospectively registered (date of registration: 06/07/2020).
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