Evidence map›Paper›PMID 40357385›Full record

ArticleClinical case reports2025

Cocaine-Induced Apoplexy of a GH-Secreting Pituitary Tumor.

Dalia Cuenca, Latife Salame-Khouri, Daniela Shveid-Gerson, Marco Antonio Alegría-Loyola, Moises Mercado

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dalia CuencaDepartment of Medicine American British Cowdray Medical Center Mexico City Mexico.ORCID https://orcid.org/0000-0001-9961-4667
Latife Salame-KhouriDepartment of Neurology Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán Mexico City Mexico.ORCID https://orcid.org/0000-0001-6387-3624
Daniela Shveid-GersonDepartment of Medicine American British Cowdray Medical Center Mexico City Mexico.ORCID https://orcid.org/0000-0002-9501-3060
Marco Antonio Alegría-LoyolaDepartment of Medicine American British Cowdray Medical Center Mexico City Mexico.
Moises MercadoEndocrine Research Unit, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, IMSS Mexico City Mexico.ORCID https://orcid.org/0000-0002-4748-9734

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 25-year-old previously healthy man presents to the clinic with a severe headache after cocaine consumption. Physical examination revealed acromegaloid features, and the hormonal profile revealed an IGF-1 of 308 ng/mL (40.8 nmol/L) (normal reference range 197-333 ng/mL; 17.8-45.6). An MRI showed a heterogeneous, cystic lesion of the pituitary gland with hematic contents, consistent with the diagnosis of a pituitary apoplexy. Considering the normal IGF-1 level, the patient was classified to be in remission, which deems it unnecessary to initiate pharmacologic or surgical treatment. Remission of acromegaly after a pituitary apoplexy is an extremely rare event, and pituitary apoplexy after cocaine consumption is also anecdotal. We present the first case of remission of acromegaly after a cocaine-induced pituitary apoplexy.

Indexed as

acromegalycocainegrowth hormonepituitary apoplexytumor

Identifiers

PMID40357385
PMCPMC12067553

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.