ArticleJournal of arrhythmia2025
The HFA-PEFF score and outcomes in patients with sick sinus syndrome and preserved ejection fraction after pacemaker implantation.
Article in Journal of arrhythmia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Association Between Left Ventricular Diastolic Dysfunction and Subsequent Detection of Sick Sinus Syndrome and Atrial Fibrillation in Patients With Unexplained Syncope.Journal of arrhythmia · 2026Article
- Screening for HFpEF in pacemaker patients: Study design and protocol of the PM-HFpEF study.PloS one · 2026Article
- The HFA-PEFF score and outcomes in patients with sick sinus syndrome and preserved ejection fraction after pacemaker implantation.Journal of arrhythmia · 2025Article
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Authors and funding
7 authors.
Funding
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Abstract
Background: Sick sinus syndrome (SSS) is associated with atrial fibrillation (AF) and heart failure with preserved ejection fraction (HFpEF). However, diagnosing HFpEF in patients with SSS and determining its prognosis are challenging. The European Society of Cardiology has recommended the HFA-PEFF score for HFpEF diagnosis. In this study, we utilized the HFA-PEFF score to diagnose HFpEF in patients with SSS and preserved ejection fraction, comparing the prognosis and AF burden between those diagnosed with HFpEF and those without. Methods: We identified 131 patients with symptomatic SSS and preserved ejection fraction who underwent pacemaker implantation between January 2019 and December 2021. Of these, 52 (39.7%) had an HFA-PEFF score ≥5 and met the diagnostic criteria for HFpEF. Results: Patients with HFpEF experienced more cardiovascular events (28.8% vs. 11.4%; Conclusions: Patients diagnosed with HFpEF using the HFA-PEFF score have a higher incidence of cardiovascular events and a greater AF burden within 3 years after pacemaker implantation for SSS. The HFA-PEFF score may be useful for risk stratification in these patients.
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