ArticleFrontiers in medicine2025
Effect of dexmedetomidine on the median effective concentration of ropivacaine for postoperative analgesia in transversus abdominis plane block: an up-down sequential allocation study.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- The Optimal Dose of Butorphanol Combined with Ropivacaine for Supraclavicular Brachial Plexus Block in Patients Undergoing Upper Limb Fracture Surgery: A Randomized, Double-Blind, Controlled Clinical Trial.Drug design, development and therapy · 2026Trial
- Median Effective Concentration of Ropivacaine for Ultrasound-Guided TDrug design, development and therapy · 2026Article
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Authors and funding
5 authors.
Funding
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Abstract
Background: This study aimed to observe the effect of dexmedetomidine on the median effective concentration (EC Methods: Patients undergoing elective laparoscopic cholecystectomy were randomly divided into the RD group and the R group. In the RD group, 40 mL of ropivacaine with 1 μg/kg dexmedetomidine was injected into the transverse abdominis plane, while subjects in the R group received equal volumes of ropivacaine with normal saline. When the visual analogue scale (VAS) ≤ 3 within 6 h after surgery, postoperative analgesia was assessed as effective. The probit regression was used to calculate the EC Results: The EC Conclusion: Dexmedetomidine as a local anesthetic adjuvant can reduce the EC
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