Evidence map›Paper›PMID 40357213›Full record

ArticleFrontiers in endocrinology2025

Fear of hypoglycemia: a key predictor of sleep quality among the diabetic population.

Hafiz Rashid Hussain, Nabeel Ahmed, Muhammad Waseem Akram, Faisal Gulzar, Jawad Akbar Khan, Muhammad Asad, Sana Tahseen, Tanveer Ahmed, Abdul Malik, Suhail Akhtar and 4 more

Abstract readMulticenter Study
In one paragraph

Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Hafiz Rashid HussainCollege of Pharmacy, University of Sargodha, Sargodha, Pakistan.
Nabeel AhmedCollege of Pharmacy, University of Sargodha, Sargodha, Pakistan.
Muhammad Waseem AkramSchool of Economics, University of Wollongong, Wollongong, NSW, Australia.
Faisal GulzarRai Foundation Pharmacy College, Sargodha, Pakistan.
Jawad Akbar KhanRiphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore, Pakistan.
Muhammad AsadCadson College of Pharmacy, Kharian, Pakistan.
Sana TahseenCollege of Pharmacy, University of Sargodha, Sargodha, Pakistan.
Tanveer AhmedAhmad Polyclinic and Diabetic Center, Sargodha, Pakistan.
Abdul MalikDepartment of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Suhail AkhtarDepartment of Biochemistry, A.T. Still University of Health Sciences, Kirksville, MO, United States.
Ayesha ShahidCollege of Pharmacy, University of Sargodha, Sargodha, Pakistan.
Mah NoorCollege of Pharmacy, University of Sargodha, Sargodha, Pakistan.
Maryam PervaizCollege of Pharmacy, University of Sargodha, Sargodha, Pakistan.
Muneeb Ur RahmanCollege of Pharmacy, University of Sargodha, Sargodha, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Every one in seven people with Type-I or Type-II diabetes suffers from fear of hypoglycemia (FOH). Its impact on quality of life, glycemic control, and health outcomes is well studied. However, its relationship with sleep quality remains underexplored, particularly in developing societies. We hypothesize that FOH is a key predictor of sleep quality in Type-I and Type-II patients with diabetes and, therefore, needs detailed investigation. Methods: A multicentric study was conducted across five cities and six centers of Punjab. Data from 310 diabetes patients were analyzed using the Hypoglycemia Fear Survey-II (HFS-II) Scale and the Pittsburgh Sleep Quality Index (PSQI). Statistical analyses explored subgroup variations, correlations, regression models, and receiver operator curve (ROC) estimation. Results: The study reports 57.70% of patients with poor sleep among whom 47% had elevated FOH. Sleep quality, age, gender, diabetes duration, and insulin route significantly correlated with FOH (p < 0.05), while glycemic control and insulin use did not. Binary logistics regression showed that for every one-unit increase in FOH, the odds of experiencing poor sleep increased by approximately 3.7% ( Conclusion: FOH is a key predictor of sleep quality among patients with diabetes. Healthcare providers should prioritize patient education targeting common FOH concerns and assess patients with disturbed sleep for elevated FOH levels, as it may contribute to sleep disturbances.

Indexed as

Diabetes Mellitus, Type 1Diabetes Mellitus, Type 2FearHypoglycemiaSleep QualitySleep Wake DisordersAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrognosisQuality of Lifediabetes mellitusfear of hypoglycemiaHFS-II scalePSQIquality of sleep

Identifiers

PMID40357213
PMCPMC12066330

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.