ArticleFrontiers in acoustics2025
Characterizing random complex biological media by quantifying ultrasound multiple scattering.
Article in Frontiers in acoustics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: In this Methods: Multi-element array transducers are used to record the ultrasonic Inter element Response Matrix (IRM) of scattering phantoms and of lung tissue in rodent models of pulmonary fibrosis. The distribution of singular values of the IRM in the frequency domain is then studied to quantify the multiple scattering contribution. Numerical models of scattering media, as well as gelatin-glass bead and polydimethylsiloxane phantoms with different scatterer densities, are used as a first step to demonstrate the proof of concept. Results: The results show that changes in microstructure of a complex random medium affect parameters associated with the distribution of singular values. Two metrics are proposed: Discussion: These results suggest that such parameters could be used as metrics to estimate the amount of multiple scattering in highly heterogeneous media, and that these parameters could contribute to the evaluation of structural changes in lung microstructure.
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