Evidence map›Paper›PMID 40357127›Full record

ReviewFrontiers in chemistry2025

Recent advances in glucose monitoring utilizing oxidase electrochemical biosensors integrating carbon-based nanomaterials and smart enzyme design.

Guan Guoqiang, Qu Liang, Zhao Yani, Wang Pengyun, Kong Fanzhuo, Zhang Yuyang, Lin Zhiyuan, Ni Xing, Zhang Xue, Lu Qiongya and 1 more

Abstract readReview
In one paragraph

Review in Frontiers in chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Guan GuoqiangSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang, China.
Qu LiangSchool of Food and Bioengineering, Wuhu Institute of Technology, Wuhu, China.
Zhao YaniSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang, China.
Wang PengyunSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang, China.
Kong FanzhuoSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang, China.
Zhang YuyangSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang, China.
Lin ZhiyuanSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang, China.
Ni XingSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang, China.
Zhang XueSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang, China.
Lu QiongyaSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang, China.
Zou BinSchool of Food and Biological Engineering, Jiangsu University, Zhenjiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glucose oxidase (GOx), as a molecular recognition element of glucose biosensors, has high sensitivity and selectivity advantages. As a type of biosensor, the glucose oxidase electrode exhibits advantages such as ease of operation, high sensitivity, and strong specificity, promising broad application prospects in biomedical science, the food industry, and other fields. In recent years, with the advancement of nanotechnology, research efforts to enhance the performance of GOx biosensors have primarily focused on improving the conductive properties and specific surface area of nanomaterials, while neglecting the potential to modify the structure of the core component, GOx itself, to improve biosensor performance. Rapid modification of the GOx surface through chemical modification techniques yields a new modified enzyme (mGOx). Meanwhile, composite techniques involving carbon nanomaterials can be employed to further enhance sensor performance. This article reviews the construction methods and optimization strategies of glucose oxidase electrodes in recent years, along with research progress in their application in electrochemical sensing for glucose detection, and provides an outlook for future developments.

Indexed as

carbon nanomaterialschemical modificationelectrochemical sensingglucose detectionglucose oxidase

Identifiers

PMID40357127
PMCPMC12066265

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.