ArticleCureus2025
Antibiotic Resistance and Surgical Site Infections in Free Flap Reconstruction for Head and Neck Cancer: A Retrospective Analysis From a Lower-Middle-Income Country.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Article
- Rational utilization of antibiotic prophylaxis in oral and maxillofacial surgery: a large scope review of recent data.BMC oral health · 2025Review
- Advances in Diagnosis and Treatment in Otolaryngology.Diagnostics (Basel, Switzerland) · 2025Article
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Authors and funding
6 authors.
Funding
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Abstract
objectiveThis study aimed to analyze the frequency of infection and its causative organisms, with their antibiotic susceptibility pattern, in patients who underwent free flap reconstructive surgery for head and neck cancers. METHODOLOGY: This hospital record-based cross-sectional study was conducted at Aga Khan University Hospital in Karachi, Pakistan, involving 92 patients who underwent free flap reconstruction between January 1, 2023, and December 31, 2023. Data, including demographic information, surgical specifics, and microbial profiles, were collected from patient records, with a focus on postoperative wound infections after obtaining approval. Data analysis was done using IBM SPSS Statistics for Windows, Version 23 (Released 2015; IBM Corp., Armonk, New York, United States).
resultsAmong 92 patients, 11 (11.9%) developed surgical site infections (SSIs). Male gender and age between 41 and 60 years were significantly associated with the occurrence of SSIs (p < 0.001). There was no significant relationship between age, American Society of Anesthesiologists (ASA) score, comorbidities, and flap types. Gram-negative bacteria, particularly
conclusionSSI was noted in 11.9% of the free flap population. Tailored antibiotic prophylaxis is crucial due to significant antimicrobial resistance in Gram-negative bacteria like
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