Evidence map›Paper›PMID 40357087›Full record

ArticleCureus2025

Left-Leg Apraxia and Bilateral Incoordination of the Lower Limb After Left Anterior Cerebral Artery Infarction: A Case Report.

Airi Kitamura, Hiroyuki Ohtsuka, Miku Aoyagi, Maho Noguchi, Naoyuki Motojima, Kana Sakuma, Tetsuichi Hondera, Mika Otsuki

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Airi KitamuraDepartment of Physical Therapy, Showa Medical University, Yokohama, JPN.
Hiroyuki OhtsukaGraduate School of Health Sciences, Showa Medical University, Yokohama, JPN.
Miku AoyagiCenter for Rehabilitation, Showa Medical University, Yokohama, JPN.
Maho NoguchiCenter for Rehabilitation, Showa Medical University, Yokohama, JPN.
Naoyuki MotojimaGraduate School of Health Sciences, Showa Medical University, Yokohama, JPN.
Kana SakumaDepartment of Rehabilitation Medicine, Showa Medical University, Tokyo, JPN.
Tetsuichi HonderaDivision of Health Science Education, Showa Medical University, Yokohama, JPN.
Mika OtsukiGraduate School of Health Sciences, Hokkaido University, Sapporo, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Callosal disconnection syndrome is characterized by impaired interhemispheric communication and motor coordination. Although its effects on upper limbs are well documented, reports on lower-limb function are limited, and their pathological mechanisms remain poorly understood. We describe a case involving a right-handed woman in her early 70s who presented with slurred speech and difficulty moving her feet. Magnetic resonance imaging revealed an atherothrombotic cerebral infarction affecting the splenium, body, and genu of the corpus callosum, as well as the medial region of the left frontal lobe. In addition to callosal disconnection symptoms, including impaired transfer of proprioceptive information from the fingers, left-hand apraxia, and intermanual conflict, this patient exhibited asynchrony in lower-limb movements and left lower-limb apraxia. The patient's ability to perform coordinated movements improved with repeated rehabilitation sessions. These findings suggest that corpus callosum injury plays a pivotal role in bilateral lower-limb coordination and motor control. We emphasize the need for further research to elucidate the role of the corpus callosum in lower-limb motor control.

Indexed as

bilateral lower-limb coordinationcallosal disconnection syndromecerebral infarctioncorpus callosuminterhemispheric communicationleg apraxiamotor coordinationrehabilitation

Identifiers

PMID40357087
PMCPMC12067021

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.