Evidence map›Paper›PMID 40357083›Full record

ArticleCureus2025

Euglycemic Diabetic Ketoacidosis in the Setting of Dulaglutide Use.

Niyati Patel, Anvit Reddy, Kaitlyn N Romero, Pramod Reddy

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Niyati PatelInternal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Anvit ReddyInternal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Kaitlyn N RomeroInternal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Pramod ReddyInternal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dulaglutide is a glucagon-like peptide (GLP-1) receptor agonist approved by the Food and Drug Administration in patients with type 2 diabetes mellitus (T2DM) with noted cardiovascular and renal benefits along with weight loss. Dulaglutide's most common adverse effects include fatigue, poor appetite, abdominal pain, nausea, vomiting, and diarrhea. Although typically associated with the use of sodium-glucose cotransporter-2 (SGLT2) inhibitors, there have been case reports of GLP-1 receptor agonists leading to euglycemic diabetic ketoacidosis (DKA). We present a case of dulaglutide use leading to euglycemic DKA, a rare but life-threatening adverse effect after re-initiation of the medication at a higher dose. Our patient presented with non-specific gastrointestinal symptoms and weakness, which both resolved after the initiation of an insulin drip and intravenous fluids.

Indexed as

dulaglutideeuglycemia diabetic ketoacidosisglp-1 receptor agoniststype 2 diabetes mellitusweight loss and obesity

Identifiers

PMID40357083
PMCPMC12068660

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.