Evidence map›Paper›PMID 40357074›Full record

ArticleCureus2025

Contrast Enhancement of the Olfactory Recess Using Heavily T2-Weighted 3D Fluid-Attenuated Inversion Recovery Imaging (FLAIR).

Koichiro Matsuura, Iichiro Osawa, Keita Nagawa, Shinji Kakemoto, Kaiji Inoue, Eito Kozawa

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Koichiro MatsuuraRadiology, Saitama Medical University Hospital, Saitama, JPN.
Iichiro OsawaRadiology, Saitama Medical University Hospital, Saitama, JPN.
Keita NagawaRadiology, Saitama Medical University Hospital, Saitama, JPN.
Shinji KakemotoRadiology, Saitama Medical University Hospital, Saitama, JPN.
Kaiji InoueRadiology, Saitama Medical University Hospital, Saitama, JPN.
Eito KozawaRadiology, Saitama Medical University Hospital, Saitama, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose This study aimed to assess the contrast enhancement of the olfactory recess using heavily T2-weighted 3D fluid-attenuated inversion recovery (FLAIR) imaging after intravenous gadolinium administration. Methods This retrospective study included 35 patients. The overall contrast enhancement of the bilateral olfactory recess between the precontrast, postcontrast, and 4-h delayed postcontrast T2-weighted 3D FLAIR images were subjectively evaluated. In addition, serial changes in signal intensity in the olfactory recess and other structures (other cerebrospinal fluid spaces and the pons) were objectively assessed. Results Subjective analysis showed that contrast enhancement of the olfactory recess was observed in 61 (right: 28, left: 33) and 67 (right: 32, left: 35) of 70 ears from 35 patients on postcontrast and 4-h delayed postcontrast T2-weighted 3D FLAIR images, respectively. In the objective analysis, the relative enhancement of the olfactory recess was the highest for 4-h delayed postcontrast images, followed by postcontrast images. This enhancement pattern was similar to that of the cerebrospinal fluid spaces surrounding the other cranial nerves. Conclusion The olfactory recess was enhanced using T2-weighted 3D FLAIR imaging. These findings may provide novel insights into cerebrospinal fluid and solute dynamics and may contribute to optimizing imaging protocols for evaluating related neurological disorders.

Indexed as

3d flaircontrast enhancementcribriform plateolfactory nerveolfactory recess

Identifiers

PMID40357074
PMCPMC12068933

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.