Evidence map›Paper›PMID 40356945›Full record

ArticleFrontiers in surgery2025

Fluorescein-distribution in confocal laser endomicroscopy allows for discrimination between primary brain tumours and metastases.

Maria C Brielmaier, Johannes Reifenrath, Franziska Ganster, Nicolas Pensel, Jens Gempt, Bernhard Meyer, Jürgen Schlegel, Arthur Wagner

Abstract read
In one paragraph

Article in Frontiers in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Real-timeFrontiers in oncology · 2026
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maria C BrielmaierDepartment of Neurosurgery, Universitaetsklinikum Rechts der Isar, Technical University Munich, Munich, Germany.
Johannes ReifenrathDepartment of Neuropathology, Institute of Pathology, Technical University Munich, Munich, Germany.
Franziska GansterDepartment of Neuropathology, Institute of Pathology, Technical University Munich, Munich, Germany.
Nicolas PenselDepartment of Neuropathology, Institute of Pathology, Technical University Munich, Munich, Germany.
Jens GemptDepartment of Neurosurgery, Universitaetsklinikum Rechts der Isar, Technical University Munich, Munich, Germany.
Bernhard MeyerDepartment of Neurosurgery, Universitaetsklinikum Rechts der Isar, Technical University Munich, Munich, Germany.
Jürgen SchlegelDepartment of Neuropathology, Institute of Pathology, Technical University Munich, Munich, Germany.
Arthur WagnerDepartment of Neurosurgery, Universitaetsklinikum Rechts der Isar, Technical University Munich, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Emerging digital biopsy technologies, such as confocal laser endomicroscopy (CLE), have shown how neuro-oncological surgery can be revolutionised with the help of rapid, intraoperative tissue assessment which offers a high diagnostic accuracy. For Methods: In order to understand the dyeing behaviour of SF, we initiated a pilot study, comparing the staining pattern when incubating established tumour cell lines with SF Results: Discussion: The concordant results from

Indexed as

brain-tumourconfocal laser endomicroscopydigital biopsymetastasessodium-fluorescein

Identifiers

PMID40356945
PMCPMC12066426

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.