Evidence map›Paper›PMID 40356927›Full record

ArticleFrontiers in immunology2025

Rong Wang, Yunhuan Gao, Ya Wang, Yuan Zhang, Rongcun Yang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rong WangDepartment of Immunology, Nankai University School of Medicine, Nankai University, Tianjin, China.
Yunhuan GaoDepartment of Immunology, Nankai University School of Medicine, Nankai University, Tianjin, China.
Ya WangDepartment of Immunology, Nankai University School of Medicine, Nankai University, Tianjin, China.
Yuan ZhangDepartment of Immunology, Nankai University School of Medicine, Nankai University, Tianjin, China.
Rongcun YangDepartment of Immunology, Nankai University School of Medicine, Nankai University, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipopolysaccharide (LPS, endotoxin) -mediated signaling of caspase-4 (human) and -11 (rodent) can induce the maturation of inflammatory cytokine IL-1β and cell pyroptosis, which is associated with the pathophysiology of many diseases such as obesity. However, the process by which LPS induces inflammation through caspase 4/11 is not fully understood. We found here that

Indexed as

LipopolysaccharidesMacrophagesObesityRNA, Long NoncodingAnimalsCaspases, InitiatorDiet, High-FatHumansInflammationInterleukin-1betaMaleMiceMice, Inbred C57BLPyroptosisSignal TransductionCaspases, InitiatorInterleukin-1betaLipopolysaccharidesRNA, Long Noncodingcaspase 4lncRNARIKmacrophagesobesitypyroptosis

Identifiers

PMID40356927
PMCPMC12066258

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.