Evidence map›Paper›PMID 40356851›Full record

ReviewFrontiers in oral health2025

Artificial intelligence-driven clinical decision support systems for early detection and precision therapy in oral cancer: a mini review.

Manoj Kumar Karuppan Perumal, Remya Rajan Renuka, Suresh Kumar Subbiah, Prabhu Manickam Natarajan

Abstract readReview
In one paragraph

Review in Frontiers in oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Manoj Kumar Karuppan PerumalCentre for Stem Cell Mediated Advanced Research Therapeutics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.
Remya Rajan RenukaCentre for Stem Cell Mediated Advanced Research Therapeutics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.
Suresh Kumar SubbiahCentre for Stem Cell Mediated Advanced Research Therapeutics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, Tamil Nadu, India.
Prabhu Manickam NatarajanDepartment of Clinical Sciences, College of Dentistry, Centre of Medical and Bio-Allied Health Sciences and Research, Ajman University, Ajman, United Arab Emirates.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral cancer (OC) is a significant global health burden, with life-saving improvements in survival and outcomes being dependent on early diagnosis and precise treatment planning. However, diagnosis and treatment planning are predicated on the synthesis of complicated information derived from clinical assessment, imaging, histopathology and patient histories. Artificial intelligence-based clinical decision support systems (AI-CDSS) provides a viable solution that can be implemented via advanced methodologies for data analysis, and synthesis for better diagnostic and prognostic evaluation. This review presents AI-CDSS as a promising solution through advanced methodologies for comprehensive data analysis. In addition, it examines current implementations of AI-CDSS that facilitate early OC detection, precise staging, and personalized treatment planning by processing multimodal patient information through machine learning, computer vision, and natural language processing. These systems effectively interpret clinical results, identify critical disease patterns (including clinical stage, site, tumor dimensions, histopathologic grading, and molecular profiles), and construct comprehensive patient profiles. This comprehensive AI-CDSS approach allows for early cancer detection, a reduction in diagnostic delays and improved intervention outcomes. Moreover, the AI-CDSS also optimizes treatment plans on the basis of unique patient parameters, tumor stages and risk factors, providing personalized therapy.

Indexed as

accurate treatment planningAI-CDSSearly detectionoral cancerpatient data

Identifiers

PMID40356851
PMCPMC12066789

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.