Evidence map›Paper›PMID 40356795›Full record

ReviewTherapeutic advances in endocrinology and metabolism2025

Systemic therapies for medullary thyroid carcinoma: state of the art.

Alejandro Román-González, Ines Califano, Marcio Concepción-Zavaleta, Fabian Pitoia, Sarimar Agosto Salgado

Abstract readReview
In one paragraph

Review in Therapeutic advances in endocrinology and metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alejandro Román-GonzálezSection of Endocrinology, Department of Internal Medicine, School of Medicine, Universidad de Antioquia, (University of Antioquia), Cra. 51d No. 62-29, Medellín 050001, Colombia.ORCID https://orcid.org/0000-0001-5942-1035
Ines CalifanoEndocrinology Service, Instituto de Oncología "Angel H. Roffo" (Angel H. Roffo Institute of Oncology), University of Buenos Aires, Buenos Aires, Argentina.ORCID https://orcid.org/0000-0002-7450-5832
Marcio Concepción-ZavaletaCarrrera de Medicina Humana Universidad Científica del Sur (Scientific University of the South), Lima, Peru.ORCID https://orcid.org/0000-0001-9719-1875
Fabian PitoiaDivision of Endocrinology, Hospital de Clínicas (Clinics Hospital), University of Buenos Aires, Buenos Aires, Argentina.
Sarimar Agosto SalgadoDepartment of Head and Neck-Endocrine Oncology, Moffitt Cancer Center, Tampa, FL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medullary thyroid carcinoma (MTC) is a rare neuroendocrine tumor accounting for less than 5% of all thyroid cancers. An estimated 25% of cases are familial secondary to a germline mutation on the rearranged during transfection proto-oncogene (

Indexed as

cabozantinibcalcitoninmedullary thyroid carcinomaselpercatinibvandetanib

Identifiers

PMID40356795
PMCPMC12066861

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.