Evidence map›Paper›PMID 40356605›Full record

ArticleJournal of experimental pharmacology2025

Influence of the Solvent and the Harvesting Site on the Content of Phenolic Compounds and the in Vitro Antidiabetic Potential of Leafy Stems and Roots of

Abdoul Aziz Zanté, Daouda Zoungo, Yacouba Sanou, Pawendé Kabré, Relwendé Justin Ouédraogo, Lazare Belemnaba, Lassina Ouattara, Paulin Ouoba, Georges Anicet Ouédraogo

Abstract read
In one paragraph

Article in Journal of experimental pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Abdoul Aziz ZantéEcole Doctorale Sciences Naturelles et Agronomie, Université Nazi BONI, Bobo-Dioulasso, Burkina Faso.ORCID 0000-0003-2536-8111
Daouda ZoungoEcole Doctorale Sciences Naturelles et Agronomie, Université Nazi BONI, Bobo-Dioulasso, Burkina Faso.
Yacouba SanouEcole Doctorale Sciences Naturelles et Agronomie, Université Nazi BONI, Bobo-Dioulasso, Burkina Faso.
Pawendé KabréEcole Doctorale Sciences Naturelles et Agronomie, Université Nazi BONI, Bobo-Dioulasso, Burkina Faso.
Relwendé Justin OuédraogoDépartement de la Médecine Traditionnelle, de la Pharmacopée et de la Pharmacie, Institut de Recherche en Sciences de la Santé, Ouagadougou, Burkina Faso.
Lazare BelemnabaDépartement de la Médecine Traditionnelle, de la Pharmacopée et de la Pharmacie, Institut de Recherche en Sciences de la Santé, Ouagadougou, Burkina Faso.ORCID 0000-0002-4519-2603
Lassina OuattaraEcole Doctorale Sciences Naturelles et Agronomie, Université Nazi BONI, Bobo-Dioulasso, Burkina Faso.ORCID 0000-0001-5537-5246
Paulin OuobaEcole Doctorale Sciences Naturelles et Agronomie, Université Nazi BONI, Bobo-Dioulasso, Burkina Faso.
Georges Anicet OuédraogoEcole Doctorale Sciences Naturelles et Agronomie, Université Nazi BONI, Bobo-Dioulasso, Burkina Faso.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The objective was to verify the impact of the solvent and the harvesting site on the content of phenolic compounds as well as the in vitro antidiabetic activity of leafy stems and roots of Methods: The polyphenols and total flavonoids were measured on the crude extracts, obtained after maceration for 48 hours with acetone-water 50:50 (v/v), and ethanol-water 70:30 (v/v) . These extracts were evaluated for their antioxidant properties by DPPH, ABTS, and iron reduction (FRAP) tests. Finally, the α-amylase inhibitory activity of the crude extracts was determined by the method using DNS. Results: The results show that acetone-water favors polyphenol extraction, with a maximum content of 32.62 ± 0.85 mg EAG/100 mg DE in leafy stems from Banfora (LSBaAw). In contrast, ethanol-water extracted more flavonoids, with 4.59 ± 0.02 mg EQ/100 mg DE in roots from Bobo (RBoEw). For antioxidant activity, the ethanol-water extract of Bobo leafy stems (LSBoEw) showed the highest ABTS free radical scavenging activity (81.34 ± 1.07 µg/mL). In comparison, the ethanol-water extract of Banfora roots (RBaEw) showed the best DPPH free radical scavenging activity (55.71 ± 2.48 µg/mL). On the other hand, the acetone-water extract of Banfora leafy stems (LSBaAw) showed the highest iron reduction activity (15,445.81 ± 835.75 µmol EAA/100 mg DE). Finally, the highest α-amylase inhibitory activity was observed with ethanol-water extracts from roots (RBaEw: 98.45 ± 0.38%; RBoEw: 96.56±0.31%). Conclusion: These results underline the importance of the choice of solvent, organ, and harvesting site in optimizing the use of

Indexed as

leafy stemPhyllanthus amarusrootsitesolvent

Identifiers

PMID40356605
PMCPMC12066366

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.