Evidence map›Paper›PMID 40356457›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2025

International multi-center study of middle meningeal artery embolization for chronic subdural hematoma in cancer patients: Efficacy, safety, and outcomes in a high-risk population.

Avi A Gajjar, Mohamed M Salem, Georgios S Sioutas, Rashad Jabarkheel, Okkes Kuybu, Jane Khalife, Daniel A Tonetti, Gustavo Cortez, Adam A Dmytriw, Diego Alejandro Ortega Moreno and 27 more

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In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

37 authors.

Avi A GajjarDepartment of Neurosurgery, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-3686-9413
Mohamed M SalemDepartment of Neurosurgery, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, Pennsylvania, USA.
Georgios S SioutasDepartment of Neurosurgery, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, Pennsylvania, USA.
Rashad JabarkheelDepartment of Neurosurgery, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, Pennsylvania, USA.
Okkes KuybuDepartment of Neurosurgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-0655-5755
Jane KhalifeDepartment of Neurosurgery, Cooper University Health Care, Camden, New Jersey, USA.
Daniel A TonettiDepartment of Neurosurgery, Cooper University Health Care, Camden, New Jersey, USA.
Gustavo CortezDepartment of Cerebrovascular and Endovascular Surgery, Baptist Neurological Institute and Lyerly Neurosurgery, Jacksonville, Florida, USA.
Adam A DmytriwNeuroendovascular Program, Massachusetts General Hospital & Brigham and Women's Hospital, Harvard University, Boston, MA, USA.ORCID 0000-0003-0131-5699
Diego Alejandro Ortega MorenoNeurovascular Centre, Divisions of Therapeutic Neuroradiology and Neurosurgery, St Michael's Hospital, University of Toronto, Toronto, ON, USA.
William SmithNeuroendovascular Program, Massachusetts General Hospital & Brigham and Women's Hospital, Harvard University, Boston, MA, USA.
Robert W RegenhardtNeuroendovascular Program, Massachusetts General Hospital & Brigham and Women's Hospital, Harvard University, Boston, MA, USA.
Kate T CarrollDepartment of Neurological Surgery, University of Washington, Seattle, Washington, USA.
Zachary A AbecassisDepartment of Neurological Surgery, University of Washington, Seattle, Washington, USA.
Juan Francisco Ruiz RodriguezDepartment of Neurological Surgery, University of Washington, Seattle, Washington, USA.
Oleg ShekhtmanDepartment of Neurosurgery, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-7871-9539
Alex Nguyen HoangDepartment of Neurosurgery, Baylor College of Medicine, Houston, Texas, USA.
Alexander A KhalessiDepartment of Neurosurgery, University of California-San Diego, La Jolla, California, USA.
Cordell BakerDepartment of Neurosurgery, University of Utah, Salt Lake City, Utah, USA.
Matthias MatejkaDepartment of Neurosurgery, University Hospital Salzburg, Paracelsus Medical University, Salzburg, Austria.
Nicole M CancelliereNeurovascular Centre, Divisions of Therapeutic Neuroradiology and Neurosurgery, St Michael's Hospital, University of Toronto, Toronto, ON, USA.
Christoph J GriessenauerDepartment of Neurosurgery, University Hospital Salzburg, Paracelsus Medical University, Salzburg, Austria.ORCID 0000-0002-2952-3812
Ramesh GrandhiDepartment of Neurosurgery, University of Utah, Salt Lake City, Utah, USA.ORCID 0000-0001-9000-6083
Peter KanDepartment of Neurosurgery, Baylor College of Medicine, Houston, Texas, USA.
Omar TanweerDepartment of Neurosurgery, Baylor College of Medicine, Houston, Texas, USA.
Michael R LevittDepartment of Neurological Surgery, University of Washington, Seattle, Washington, USA.
Christopher J StapletonNeuroendovascular Program, Massachusetts General Hospital & Brigham and Women's Hospital, Harvard University, Boston, MA, USA.
Vitor Mendes PereiraNeurovascular Centre, Divisions of Therapeutic Neuroradiology and Neurosurgery, St Michael's Hospital, University of Toronto, Toronto, ON, USA.
Brian JankowitzDepartment of Neurosurgery, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-9306-0763
Howard A RiinaDepartment of Neurosurgery, NYU Langone Medical Center, New York, New York, USA.
Aman B PatelNeuroendovascular Program, Massachusetts General Hospital & Brigham and Women's Hospital, Harvard University, Boston, MA, USA.
Ricardo HanelDepartment of Cerebrovascular and Endovascular Surgery, Baptist Neurological Institute and Lyerly Neurosurgery, Jacksonville, Florida, USA.
Ajith J ThomasDepartment of Neurosurgery, Cooper University Health Care, Camden, New Jersey, USA.
Michael J LangDepartment of Neurosurgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Bradley A GrossDepartment of Neurosurgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Jan-Karl BurkhardtDepartment of Neurosurgery, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, Pennsylvania, USA.
Visish M SrinivasanDepartment of Neurosurgery, Hospital of the University of Pennsylvania, Penn Medicine, Philadelphia, Pennsylvania, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundMiddle meningeal artery embolization (MMAE) is a promising treatment for chronic subdural hematoma (cSDH). Cancer patients are at risk for cSDH due to thrombocytopenia. The efficacy of MMAE in this population has not been studied.MethodsWe conducted a retrospective analysis of 76 patients who underwent 94 MMAEs for cSDH at 12 tertiary centers across North America and Europe between February 2018 and January 2023. We analyzed patient demographics, clinical profiles, procedural details, and outcomes. The primary outcome was cSDH progression, while secondary outcomes included radiographic resolution, mortality, 90-day functional outcomes, functional improvement, and procedural complications.ResultsRadiographic improvement occurred in 88.5% of patients, and technical success was achieved in 96.8%, with comparable rates between the MMAE-only and MMAE + surgery groups. Complications occurred in five patients (5.3%), with no significant difference between groups (6.0% in MMAE vs. 3.7% in MMAE + surgery,

Indexed as

cancerchronic subdural hematomacSDHMiddle meningeal artery embolizationMMAEthrombocytopenia

Identifiers

PMID40356457
PMCPMC12075151

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.