Evidence map›Paper›PMID 40356220›Full record

ArticleActa anaesthesiologica Scandinavica2025

The 1-Year Functional Recovery From Severe COVID-19 in a Swedish Working-Age Cohort.

Björn Ahlström, Robert Frithiof, Michael Marks-Hultström, Ing-Marie Larsson, Gunnar Strandberg, Miklos Lipcsey

Registry-linked trialAbstract read
In one paragraph

Article in Acta anaesthesiologica Scandinavica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05054608 (Long Term Outcome in ICU Treated COVID-19), which is not on this map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05054608 completednot on this map

Long Term Outcome in ICU Treated COVID-19: Return to Work

TypeobservationalSponsorUppsala UniversityRan2021 to 2021Enrolled13,537ConditionsCovid19ArmsNo intervention
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Björn AhlströmAnesthesiology and Intensive Care, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.ORCID 0000-0001-9287-3607
Robert FrithiofAnesthesiology and Intensive Care, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.ORCID 0000-0003-2278-7951
Michael Marks-HultströmAnesthesiology and Intensive Care, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.ORCID 0000-0003-4675-1099
Ing-Marie LarssonAnesthesiology and Intensive Care, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Gunnar StrandbergAnesthesiology and Intensive Care, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Miklos LipcseyAnesthesiology and Intensive Care, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.

Funding

AFA FörsäkringAkademiska University HospitalThe healthcare Region Dalarna
6 · The paper itself

Abstract

backgroundLong-term symptoms are common after the acute phase of COVID-19. We hypothesized that sick leave as an estimate of functional recovery, adjusted for confounding, differs between intensive care unit (ICU) and hospitalized COVID-19 patients and population controls.

methodsIn this cohort study, we identified all working-age individuals with COVID-19 admitted to ICUs or hospitals until July 20, 2020 from national registries. Matched population controls were randomly assigned to each ICU patient. Using logistic regression to adjust for confounding, we compared ICU patients to hospital patients and population controls on the number of sick leave-free days alive during the first year after hospital discharge and the proportion of alive individuals on sick leave after 1 year.

resultsWe included 1020 COVID-19 ICU patients, 5306 COVID-19 hospital patients, and 4387 population controls. The ICU patients had a median of 271 (interquartile range, 33-349) sick leave-free days alive, while hospital patients had 354 (334-365) and population controls 365 (365-365). ICU patients had an odds ratio (OR) of 0.14 (0.12-0.16, 95% confidence interval) compared to hospital patients, and 0.02 (0.02-0.03, both p < 0.001) compared to population controls for at least one more sick leave-free day alive. Being on sick leave 1 year after inclusion had similar but inverse ORs.

conclusionThis national cohort study, in ICU and hospitalized patients with COVID-19, shows that the severity of COVID-19 disease, functional and health status before COVID-19, and demographic factors had a major impact on recovery.

trial registrationNCT05054608.

Indexed as

COVID-19Recovery of FunctionSick LeaveAdultCohort StudiesFemaleHospitalizationHumansIntensive Care UnitsMaleMiddle AgedRegistriesSwedencritical carefunctional recoveryhospital admissionrecovery COVID‐19sick leave

Identifiers

PMID40356220
PMCPMC12069831

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.