ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2025
Evaluating linked ICD-10 Medicare claims data as a method of dementia case ascertainment in research settings.
Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Identification of prevalent dementia in Medicare Advantage encounters, compared with rigorous cohort assessments.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- Comparison of Claims-Based Algorithms for Dementia Identification: A Cross-Sectional Analysis of the National Health and Aging Trends Study (NHATS).Journal of the American Geriatrics Society · 2026Article
- Cardiovascular Disease Subtypes and Alzheimer's Disease: Phenotypic and Genetic Associations in the UK Biobank and All of Us Research Program.Journal of the American Heart Association · 2026Article
- Article
- Egg Intake and the Incidence of Alzheimer's Disease in the Adventist Health Study-2 Cohort Linked with Medicare Data.The Journal of nutrition · 2026Article
- Plant-Based Dietary Patterns and Risk of Alzheimer Disease and Related Dementias in the Multiethnic Cohort Study.Neurology · 2026Article
- Performance of ICD-10 code-based dementia case definition in the Health and Retirement Study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Detecting multimorbidity patterns in Alzheimer's disease using unsupervised machine learning: A nationwide emergency department study (2007-2022).Journal of Alzheimer's disease : JAD · 2026Article
- The Brain Vulnerability Index: Development and Validation of a Machine Learning-Derived, Community-Informed Geospatial Risk Score for Cognitive Impairment.Research square · 2026Article
- Leveraging electronic health records to examine differential clinical outcomes in people with Alzheimer's disease.Communications medicine · 2026Article
- Predicting Mortality and Costs After Emergency Department Visits by People With Dementia: Timing and Location Matter.Journal of the American Geriatrics Society · 2026Article
- Performance of ICD10 Code-Based Dementia Case Definition in the Health and Retirement Study.medRxiv : the preprint server for health sciences · 2026Article
- Communication Surrounding Treatment Preferences for Older Adults With Dementia During Emergency Medical Services Response.Journal of the American Geriatrics Society · 2026Article
- Comparative risk of dementia between direct oral anticoagulants and warfarin after atrial fibrillation related ischemic stroke.Frontiers in aging neuroscience · 2026Article
- Novel predictors of Alzheimer's disease in Down syndrome identified using machine learning.Journal of Alzheimer's disease : JAD · 2025Article
- Evaluating linked ICD-10 Medicare claims data as a method of dementia case ascertainment in research settings.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
13 authors.
Funding
Abstract
introductionUS Medicare claims can be used to identify dementia cases for research. Our objective was to evaluate the performance of International Classification of Diseases, 10th Revision (ICD-10) code definitions versus research-based dementia ascertainment.
methodsParticipants of five Rush Alzheimer's Disease Center (RADC) cohorts with study visits between October 2015 and December 2019 and fee-for-service Medicare contributed observations. For each observation, we compared research-based dementia status to dementia status based on six ICD-10 code definitions.
resultsA total of 1869 participants contributed 5309 observations (mean age 82.9 years, 21.0% Black, 9.3% met research-based dementia criteria). The accuracy of ICD-10 code definitions was high (87%-90%); five of six code definitions favored specificity over sensitivity. All ICD-10 code definitions were less accurate among subgroups defined by older age, minoritized race, increased depressive symptoms, and history of stroke. DISCUSSION: Performance of ICD-10 code definitions mirrored that of ICD-9 code definitions. Awareness of differential performance by participant characteristics can improve the robustness of research. HIGHLIGHTS: We report the performance of the International Classification of Diseases, 10th Revision (ICD-10) code versus research-based dementia ascertainment. ICD-10 performed worse with age, depressive symptoms, minoritized race, and stroke. Awareness of accuracy and differential performance can improve research robustness.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.