Evidence map›Paper›PMID 40355832›Full record

ArticleJournal of the American Chemical Society2025

A Catalytic Asymmetric Intramolecular [4 + 1]-Cycloaddition for the Total Synthesis of Terpene Alkaloid Natural Products.

Wen Xiu, Calvin D Huffman, William A Swann, Christina W Li, Christopher Uyeda

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wen XiuDepartment of Chemistry, Purdue University, West Lafayette 47907, Indiana, United States.
Calvin D HuffmanDepartment of Chemistry, Purdue University, West Lafayette 47907, Indiana, United States.
William A SwannDepartment of Chemistry, Purdue University, West Lafayette 47907, Indiana, United States.
Christina W LiDepartment of Chemistry, Purdue University, West Lafayette 47907, Indiana, United States.ORCID 0000-0002-3538-9955
Christopher UyedaDepartment of Chemistry, Purdue University, West Lafayette 47907, Indiana, United States.ORCID 0000-0001-9396-915X

Funding

Transition Metal Catalyzed Reductive Carbene Transfer ReactionsR35GM124791 · NIGMS · PURDUE UNIVERSITY · PI Christopher Uyeda · 2017 to 2026
$4.2M
Heterogeneous Directed Hydrogenation of Arenes and Olefins with Chemo- and StereoselectivityR35GM151120 · NIGMS · PURDUE UNIVERSITY · PI Christina W Li · 2023 to 2026
$1.5M
NIGMS NIH HHS R35 GM124791NIGMS NIH HHS R35 GM151120
6 · The paper itself

Abstract

Intramolecular Diels-Alder reactions are privileged strategic disconnections in the synthesis of polycyclic natural products containing six-membered rings. The analogous [4 + 1]-cycloaddition may possess comparable utility in addressing [

Identifiers

PMID40355832
PMCPMC12136059

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.