Evidence map›Paper›PMID 40355785›Full record

ArticleJournal of neuro-oncology2025

Evaluating safety and feasibility of same-day discharge after laser interstitial thermal therapy: a pilot study with a matched control group.

Adham M Khalafallah, Nikola Susic, Khushi H Shah, Maxon V Knott, Chandler N Berke, Muhammet E Gurses, Victor M Lu, Michael E Ivan, Ricardo J Komotar, Ashish H Shah

Registry-linked trialAbstract read
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In one paragraph

Article in Journal of neuro-oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07104890 (Evaluation of Enhanced Recovery After Surgery), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07104890 nacompletednot on this map

Evaluation of Enhanced Recovery After Surgery (ERAS) Protocol on Postoperative Recovery in Elective Cesarean Sections

TypeinterventionalSponsorHavva Betül BacakRan2022 to 2022Enrolled84ConditionsElective Cesarean Section, Postoperative Recovery, Enhanced Recovery After Surgery (ERAS)ArmsEnhanced Recovery After Surgery (ERAS) Protocol, which includes early oral intake, early mobilization, opioid-sparing multimodal analgesia, prophylactic antiemetics, early urinary catheter removal, an
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Adham M KhalafallahDepartment of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, USA. Adham.Khalafallah@jhsmiami.org.
Nikola SusicDepartment of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Khushi H ShahDepartment of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Maxon V KnottDepartment of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Chandler N BerkeDepartment of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Muhammet E GursesDepartment of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Victor M LuDepartment of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Michael E IvanDepartment of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Ricardo J KomotarDepartment of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.
Ashish H ShahDepartment of Neurological Surgery, University of Miami Miller School of Medicine, Miami, FL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeLaser interstitial thermal therapy (LITT) is a minimally invasive treatment for intracranial tumors. Enhanced recovery after surgery (ERAS) protocols aim to optimize patient outcomes, and same-day discharge (SDD) is an emerging strategy to improve efficiency while maintaining safety. This pilot study evaluates the feasibility and safety of SDD following LITT.

methodsA retrospective review was conducted of patients who underwent LITT with planned SDD between May 2023 and June 2024 at our institution. Patients successfully discharged on the same day (study group) were match-paired 1:3 based on age, gender, and pathology, with patients discharged on post-ablation day 1 (control group) between January 2014 and April 2023. Demographic, perioperative, and treatment outcomes were compared.

resultsSDD was achieved in 10 patients (mean age 56.80 ± 11.43 years, 70% males), compared to 30 controls (mean age 58.87 ± 12.23, 70% males). SDD patients had a significantly shorter observation period (p < 0.001). No differences were observed in postoperative edema (p = 0.640), midline shift (p = 0.195), Karnofsky Performance Status (KPS) at follow-up (p = 0.999), 30-day postoperative complications (p = 0.620), 30-day neurosurgical complications (p = 0.999), 30-day readmission (p = 0.584), 30-day neurosurgical readmission (p = 0.999), or 90-day mortality (p = 0.999) between groups.

conclusionOur findings suggest that SDD following LITT is safe and feasible for appropriately selected patients. Rigorous patient selection and optimized perioperative protocols facilitate expedited recovery without compromising safety.

Indexed as

Brain NeoplasmsLaser TherapyPatient DischargeAdultAgedCase-Control StudiesFeasibility StudiesFemaleHumansMaleMiddle AgedPilot ProjectsPostoperative ComplicationsRetrospective StudiesTreatment OutcomeIntracranialLaser interstitial thermal therapyLength of stayProof-of-conceptSame-day discharge

Identifiers

PMID40355785

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.