Evidence map›Paper›PMID 40355767›Full record

ReviewRice (New York, N.Y.)2025

Lesion Mimic Mutant: An Ideal Genetic Material for Deciphering the Balance Between Plant Immunity and Growth.

Huilin Chen, Letong Liu, Qiguang Zhou, Yulin Zhu, Ziwen Gao, Taotao Zhu, Jie Huang, Mengxue Du, Yong Song, Lingzhi Meng

Abstract readReview
In one paragraph

Review in Rice (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Red Light Triggers Lesion Formation in thePlants (Basel, Switzerland) · 2026
    Article
  5. Transcriptomic and metabolomic analyses revealFrontiers in plant science · 2026
    Article
  6. Article
  7. Lesion mimic geneFrontiers in plant science · 2025
    Article
  8. Proteomic analysis of rice mutantFrontiers in plant science · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Huilin Chen *College of Agriculture and Biology of Liaocheng University, Liaocheng, 252000, China.
Letong Liu *College of Agriculture and Biology of Liaocheng University, Liaocheng, 252000, China.
Qiguang Zhou *College of Agriculture and Biology of Liaocheng University, Liaocheng, 252000, China.
Yulin ZhuCollege of Agriculture and Biology of Liaocheng University, Liaocheng, 252000, China.
Ziwen GaoCollege of Agriculture and Biology of Liaocheng University, Liaocheng, 252000, China.
Taotao ZhuCollege of Agriculture and Biology of Liaocheng University, Liaocheng, 252000, China.
Jie HuangLiaocheng Academy of Agricultural Sciences, Liaocheng, 252000, China.
Mengxue DuCollege of Agriculture and Biology of Liaocheng University, Liaocheng, 252000, China. dumengxue1220@163.com.
Yong SongCollege of Agriculture and Biology of Liaocheng University, Liaocheng, 252000, China. songyong@lcu.edu.cn.
Lingzhi MengCollege of Agriculture and Biology of Liaocheng University, Liaocheng, 252000, China. menglingzhi6@163.com.

Funding

Doctoral Research Startup Funds, Liaocheng University 318052165Luxi Agricultural Standardization Internship Base Project K20LC501Open Project of Liaocheng University Landscape Architecture Discipline 31946221217Shandong Provincial Natural Science Foundation K22LB56Youth innovation team project of Shandong Province 2023KJ208
6 · The paper itself

Abstract

Lesion mimic mutants (LMMs) form hypersensitive response (HR)-like lesions, a form of programmed cell death (PCD), in the absence of pathogens, that often confer durable and broad-spectrum disease resistance, representing a potential source for breeding resistance. However, most LMM plants have significant growth retardation including cell death, leaf senescence, damaged chloroplast structure, decreased chlorophyll contents, and undesirable agronomic traits. Therefore, LMMs represent ideal genetic materials to decipher interactions between defense signaling and programmed cell death, and growth. Many LMMs have been identified in rice, and at least 61 genes have been cloned and functionally confirmed. LMM genes are reported to participate in various regulation pathways, including gene transcription and protein translation, ubiquitin-proteasome pathway, protein phosphorylation, vesicle trafficking, metabolic pathways, and phytohormone signaling, highlighting the complexity of regulatory mechanisms. This review discusses recent progress on characteristics of rice LMM and mechanisms of LMM gene regulation, and suggests directions for future theoretical research and the potential use of LMMs in rice breeding.

Indexed as

Cell deathImmunityLesion mimic mutantRegulation mechanismRice

Identifiers

PMID40355767
PMCPMC12069192

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.