Evidence map›Paper›PMID 40355762›Full record

ArticleAnalytical and bioanalytical chemistry2025

Mid-IR laser measurement of acetaldehyde in the headspace gas of cell culture media samples from growth of breast cancer cells in hydrogel scaffolds.

Parker Bryant, Patrick McCann, Khosrow Namjou, Vassilios Sikavitsas, Roger Harrison

Abstract read
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In one paragraph

Article in Analytical and bioanalytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Parker BryantSchool of Chemical, Biological and Materials Engineering, Gallogly College of Engineering, The University of Oklahoma, Norman, USA.
Patrick McCannSchool of Electrical and Computer Engineering, Gallogly College of Engineering, The University of Oklahoma, 110 West Boyd Street, Norman, OK, 73019-1102, USA. pmccann@ou.edu.
Khosrow NamjouSchool of Electrical and Computer Engineering, Gallogly College of Engineering, The University of Oklahoma, 110 West Boyd Street, Norman, OK, 73019-1102, USA.
Vassilios SikavitsasSchool of Chemical, Biological and Materials Engineering, Gallogly College of Engineering, The University of Oklahoma, Norman, USA.
Roger HarrisonSchool of Chemical, Biological and Materials Engineering, Gallogly College of Engineering, The University of Oklahoma, Norman, USA.

Funding

Oklahoma Center for the Advancement of Science and Technology HR20-129
6 · The paper itself

Abstract

A mid-IR laser absorption spectrometer configured with an interband cascade laser (ICL) was used to measure acetaldehyde concentrations in the headspace gas of cell culture media samples obtained from the culturing of breast cancer cells in a flow perfusion bioreactor. Measurements were performed by bubbling lab air through a media sample and passing the exhaust gas through a long optical path gas cell where rotational-vibrational modes of acetaldehyde were excited by the ICL. Acetaldehyde concentrations were determined from peak-to-peak voltages for the two strongest acetaldehyde absorption features within a spectral region spanning 1770.20 cm

Indexed as

AcetaldehydeBreast NeoplasmsCulture MediaHydrogelsCell Culture TechniquesCell Line, TumorFemaleGasesHumansLasersSpectrophotometry, InfraredAcetaldehydeCulture MediaGasesHydrogelsAcetaldehydeBreast cancer ell culturesCancer cell metabolismFlow perfusion bioreactorHypoxia inducible factor 1-alphaInterband cascade laserLaser absorption spectroscopyMid-infrared

Identifiers

PMID40355762

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.