Evidence map›Paper›PMID 40355737›Full record

ArticleSurgical endoscopy2025

Prediction of endoscopic restenosis after endoscopic balloon dilation in patients with Crohn's disease: a machine learning approach.

Tao Su, Yi Lu, Nan Lan, Hongzhen Wu, Luying Wu, Min Zhang, Xiaoling Wang, Jiachen Sun, Jiayin Yao, Min Zhi

Abstract read
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tao Su *Department of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-Sen University, 26th Yuancun the Second Road, Guangzhou, 510655, Guangdong Province, China.ORCID http://orcid.org/0000-0003-2051-8029
Yi Lu *Department of Gastrointestinal Endoscopy, The Sixth Affiliated Hospital, Sun Yat-Sen University, 26th Yuancun the Second Road, Guangzhou, 510655, Guangdong Province, China.
Nan Lan *Liver and Digestive Disease Institute, Department of Medicine, Columbia Irving Medical Center, New York, NY, 10025, USA.
Hongzhen WuDepartment of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-Sen University, 26th Yuancun the Second Road, Guangzhou, 510655, Guangdong Province, China.
Luying WuDepartment of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-Sen University, 26th Yuancun the Second Road, Guangzhou, 510655, Guangdong Province, China.
Min ZhangDepartment of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-Sen University, 26th Yuancun the Second Road, Guangzhou, 510655, Guangdong Province, China.
Xiaoling WangDepartment of Clinical Nutrition, The Eighth Affiliated Hospital, Sun Yat-Sen University, Shenzhen, Guangdong Province, China.
Jiachen SunDepartment of Gastrointestinal Endoscopy, The Sixth Affiliated Hospital, Sun Yat-Sen University, 26th Yuancun the Second Road, Guangzhou, 510655, Guangdong Province, China. sunjch8@mail.sysu.edu.cn.
Jiayin YaoDepartment of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-Sen University, 26th Yuancun the Second Road, Guangzhou, 510655, Guangdong Province, China. yjyin@mail3.sysu.edu.cn.
Min ZhiDepartment of Gastroenterology, The Sixth Affiliated Hospital, Sun Yat-Sen University, 26th Yuancun the Second Road, Guangzhou, 510655, Guangdong Province, China. zhimin@mail.sysu.edu.cn.

Funding

The Sixth Affiliated Hospital of Sun Yat-Sen University Clinical Research-"1010" Program 1010CG(2024)-08The Sixth Affiliated Hospital of Sun Yat-Sen University Clinical Research-"1010" Program 1010PY (2022)-16
6 · The paper itself

Abstract

backgroundEndoscopic balloon dilation (EBD) is recognized as a minimally invasive and effective procedure for managing intestinal stenosis in patients with Crohn's disease (CD). It offers an alternative to surgery and has been shown to improve the quality of life for these patients by reducing the need for more aggressive interventions. This study aimed to evaluate factors associated with endoscopic restenosis after EBD and construct a prognostic model.

methodsWe retrospectively collected and analyzed data on patients receiving EBD treatment at the Sixth Affiliated Hospital of Sun Yat-sen University from 2013 to 2024. Seven machine learning (ML) algorithms were used to construct prognostic models. Subsequently, we conducted comparative tests on the performance of the models to ensure accuracy and reliability.

resultsA total of 135 patients were included in the statistical analysis. 53% occurred endoscopic restenosis, with an average restenosis time of 183 days. COX and logistic regression analysis showed that 4 features including ever-use glucocorticoids, stenosis position, technical success, and albumin level were associated with restenosis risk. When comparing different ML models, CoxPH and LASSO models performed better on various evaluation metrics, including C-index which was greater than 0.7 in the train and test set. Based on SHapley Additive exPlanations (SHAP), stenosis position, balloon diameter, and albumin level were identified as the top 3 important features associated with prognosis.

conclusionThe ML-based prognostic model has good predictive performance and can accurately assess the risk of endoscopic restenosis after EBD treatment.

Indexed as

Crohn DiseaseDilatationIntestinal ObstructionMachine LearningAdultConstriction, PathologicFemaleHumansMaleMiddle AgedPrognosisRecurrenceRetrospective StudiesYoung AdultCrohn’s diseaseEndoscopic balloon dilationMachine learningPrognostic model

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.