Evidence map›Paper›PMID 40355677›Full record

ReviewCellular and molecular life sciences : CMLS2025

Aging and chronic inflammation: impacts on olfactory dysfunction-a comprehensive review.

Yingqi Xie, Shenglei Wang, Xudong Cha, Fengzhen Li, Zengyi Xu, Jian Wu, Huanhai Liu, Wenwen Ren

Abstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Construction ofiScience · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Modulation of Aging Diseases via RAGE Targets: A Dietary Intervention Review.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yingqi XieDepartment of Otolaryngology, The Second Affiliated Hospital of the Naval Medical University, Shanghai Changzheng Hospital, Shanghai, China.ORCID http://orcid.org/0009-0002-9291-0548
Shenglei WangDepartment of Otolaryngology, The Second Affiliated Hospital of the Naval Medical University, Shanghai Changzheng Hospital, Shanghai, China.
Xudong ChaDepartment of Otolaryngology, The Second Affiliated Hospital of the Naval Medical University, Shanghai Changzheng Hospital, Shanghai, China.
Fengzhen LiDepartment of Otolaryngology, The Second Affiliated Hospital of the Naval Medical University, Shanghai Changzheng Hospital, Shanghai, China.
Zengyi XuDepartment of Otolaryngology, The Second Affiliated Hospital of the Naval Medical University, Shanghai Changzheng Hospital, Shanghai, China.
Jian WuDepartment of Otolaryngology, The Second Affiliated Hospital of the Naval Medical University, Shanghai Changzheng Hospital, Shanghai, China. jianwu2008@126.com.
Huanhai LiuDepartment of Otolaryngology, The Second Affiliated Hospital of the Naval Medical University, Shanghai Changzheng Hospital, Shanghai, China. liuhuanhaiok@126.com.
Wenwen RenDepartment of Otolaryngology, The Second Affiliated Hospital of the Naval Medical University, Shanghai Changzheng Hospital, Shanghai, China. wenwenren@smmu.edu.cn.

Funding

Innovative Research Group Project of the National Natural Science Foundation of China 82271136Innovative Research Group Project of the National Natural Science Foundation of China U23A20439
6 · The paper itself

Abstract

Olfactory dysfunction (OD) is a common nasal disease, particularly prevalent among the elderly population, significantly impacting the affected individuals' quality of life. This review focuses on the influence of aging and chronic inflammation on olfactory dysfunction, presenting insights from both the peripheral and central olfactory systems. By exploring the molecular mechanisms and pathological changes underlying the occurrence of olfactory dysfunction in relation to age-related diseases and chronic inflammation conditions, we aim to provide a comprehensive theoretical foundation for further research and offer valuable insights for more effective treatment of olfactory dysfunction.

Indexed as

AgingInflammationOlfaction DisordersAnimalsChronic DiseaseHumansQuality of LifeSmellAgingChronic InflammationOlfactory DysfunctionOlfactory EpitheliumPathogenesisTreatment

Identifiers

PMID40355677
PMCPMC12069206

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.