Evidence map›Paper›PMID 40355625›Full record

ArticleNature chemistry2025

Exo-templating via pseudorotaxane formation reduces pathway complexity in the multicomponent self-assembly of M

T Bouwens, E O Bobylev, L S D Antony, D A Poole, E Alarcón-Lladó, S Mathew, J N H Reek

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Article in Nature chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

T Bouwensvan 't Hoff Institute for Molecular Sciences, Universiteit van Amsterdam, Amsterdam, the Netherlands.ORCID http://orcid.org/0000-0003-4754-8930
E O Bobylevvan 't Hoff Institute for Molecular Sciences, Universiteit van Amsterdam, Amsterdam, the Netherlands.ORCID http://orcid.org/0000-0002-1563-0190
L S D AntonyAMOLF, Amsterdam, the Netherlands.ORCID http://orcid.org/0000-0002-7682-2911
D A Poolevan 't Hoff Institute for Molecular Sciences, Universiteit van Amsterdam, Amsterdam, the Netherlands.ORCID http://orcid.org/0000-0002-5065-4112
E Alarcón-Lladóvan 't Hoff Institute for Molecular Sciences, Universiteit van Amsterdam, Amsterdam, the Netherlands.ORCID http://orcid.org/0000-0001-7317-9863
S Mathewvan 't Hoff Institute for Molecular Sciences, Universiteit van Amsterdam, Amsterdam, the Netherlands.ORCID http://orcid.org/0000-0003-2480-3222
J N H Reekvan 't Hoff Institute for Molecular Sciences, Universiteit van Amsterdam, Amsterdam, the Netherlands. j.n.h.reek@uva.nl.ORCID http://orcid.org/0000-0001-5024-508X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Selective formation of multicomponent structures via the self-assembly of numerous building blocks is ubiquitous in biological systems but challenging to emulate synthetically. More components introduce additional possibilities for kinetic intermediates with trap-state ability, hampering access to desired products. In covalent chemistry, templates, reagents and catalysts are applied to create alternative pathways for desired product formation. Analogously, we enlist exo-templating to mould the formation of large, multicomponent supramolecular structures. Specifically, a charged ring docks at 1,5-dioxynaphthalene stations within exo-functionalized building blocks to promote formation of cuboctahedral Pd

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.