Evidence map›Paper›PMID 40355600›Full record

ArticleScientific reports2025

Novel Flexible Ureteroscopic System for intrarenal pelvic and intracaliceal pressure measurement in porcine models.

Yaoji Yuan, Peiying Chen, Yuyu Xu, Rui Zhu, Yu Gan, Zhiduan Cai, Wenjun Luo, Haoran Wang, Yuxuan Du, Xin Wei and 3 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yaoji Yuan *Department of Urology, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510700, China.
Peiying Chen *Department of Anesthesiology, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Yuyu Xu *Department of Urology, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510700, China.
Rui ZhuDepartment of Urology, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510700, China.
Yu GanDepartment of Urology, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510700, China.
Zhiduan CaiDepartment of Urology, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510700, China.
Wenjun LuoDepartment of Urology, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510700, China.
Haoran WangDepartment of Urology, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510700, China.
Yuxuan DuDepartment of Urology, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510700, China.
Xin WeiDepartment of Urology, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510700, China.
Liuqiang LiDepartment of Urology, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510700, China.
Dehui LaiDepartment of Urology, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510700, China. dehuilai@hotmail.com.
Guibin XuDepartment of Urology, The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510700, China. uro_xgb@163.com.

Funding

Characteristic Technology Project of Guangzhou Municipal Health Commission 2019TS38, 2023C-TS50Key Clinical Specialty Project of Guangzhou Medical University 2020Practice Teaching Base for Integration of Science, Industry and Education 2023ZLGC117, 2024KCJJD005
6 · The paper itself

Abstract

This study evaluates the consistency between intrarenal pelvic pressures (IPP) and intracaliceal pressures (ICP) and explores the impacts of irrigation flow rate (IFR) and ureteral access sheath (UAS) position on ICP using a novel Flexible Ureteroscope Pressure Measurement System. Six pigs with 12 kidneys were included in this study under general anesthesia. The IPP and ICP were measured using the Flexible Ureteroscopic Pressure Measurement System under varying UAS positions and IFRs. The 12/14Fr UAS was sequentially placed in the upper, middle, and lower segments of the porcine ureters. The irrigation pump was set to cumulative flow rates of 20, 30, 40, and 50 mL/min. Hemodynamic parameters were monitored using the Edwards Lifesciences monitoring system. The experiment was successfully completed in 10 kidneys. One kidney failed due to issues with UAS placement, and another was penetrated by the UAS. No significant difference was observed between the middle calyx ICP and IPP. ICP in the upper and lower calyces was higher than IPP, with the discrepancy being minor at 20 or 30 mL/min IFR but significant at higher IFRs of 40 and 50 mL/min. The ICP increased with higher IFRs and when the UAS was set in the low ureteral segment. Under the same IFR and UAS position, ICP varied among the three calyces (lower calyx > upper calyx > middle calyx). The Edwards Lifesciences monitoring system accurately measured hemodynamic parameters, which remained stable even at an IFR of 50 mL/min. The Flexible Ureteroscopic Pressure Measurement System can be used to measure the IPP and ICP. These pressures were not consistent across different IFRs and UAS positions. The highest ICP was observed in the lower calyx.

Indexed as

KidneyKidney PelvisUreteroscopesUreteroscopyAnimalsHemodynamicsModels, AnimalPressureSwineUreterFlexible ureteroscopeHemodynamicIntracaliceal pressureIntrarenal pelvic pressurePorcine

Identifiers

PMID40355600
PMCPMC12069519

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.