Evidence map›Paper›PMID 40355438›Full record

ArticleMicrosystems & nanoengineering2025

Stretchable multifunctional wearable system for real-time and on-demand thermotherapy of arthritis.

Zehan Liu, Xihan Wang, Yiyang He, Weiqiang Hong, Peng Sun, Weitao Liu, Dong Ye, Zhuoqing Yang, Xuewen Wang, Mengxi Wu and 2 more

Abstract read
In one paragraph

Article in Microsystems & nanoengineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Metamaterials from Plasma-Treated Block Copolymer Monolith.ACS applied materials & interfaces · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zehan LiuState Key Laboratory of High-performance Precision Manufacturing, Dalian University of Technology, 116024, Dalian, Liaoning, China.
Xihan WangState Key Laboratory of High-performance Precision Manufacturing, Dalian University of Technology, 116024, Dalian, Liaoning, China.
Yiyang HeState Key Laboratory of High-performance Precision Manufacturing, Dalian University of Technology, 116024, Dalian, Liaoning, China.
Weiqiang HongState Key Laboratory of High-performance Precision Manufacturing, Dalian University of Technology, 116024, Dalian, Liaoning, China.
Peng SunState Key Laboratory of High-performance Precision Manufacturing, Dalian University of Technology, 116024, Dalian, Liaoning, China.
Weitao LiuState Key Laboratory of High-performance Precision Manufacturing, Dalian University of Technology, 116024, Dalian, Liaoning, China.
Dong YeState Key Laboratory of Digital Manufacturing Equipment and Technology, Huazhong University of Science and Technology, 430074, Wuhan, China.
Zhuoqing YangNational Key Laboratory of Science and Technology on Micro and Nano Fabrication School of Electronic Information and Electrical Engineering, Shanghai Jiao Tong University, 200240, Shanghai, China.ORCID http://orcid.org/0000-0002-9635-6145
Xuewen WangInstitute of Flexible Electronics, Northwestern Polytechnical University, 710072, Xi'an, China.ORCID http://orcid.org/0000-0002-9689-6678
Mengxi WuState Key Laboratory of High-performance Precision Manufacturing, Dalian University of Technology, 116024, Dalian, Liaoning, China. mengxiwu@dlut.edu.cn.ORCID http://orcid.org/0000-0003-0086-5349
Liding WangState Key Laboratory of High-performance Precision Manufacturing, Dalian University of Technology, 116024, Dalian, Liaoning, China.
Junshan LiuState Key Laboratory of High-performance Precision Manufacturing, Dalian University of Technology, 116024, Dalian, Liaoning, China. liujs@dlut.edu.cn.ORCID http://orcid.org/0000-0002-9087-5518

Funding

National Natural Science Foundation of China (National Science Foundation of China) U23A20362, 51875083
6 · The paper itself

Abstract

Thermotherapy is a conventional and effective physiotherapy for arthritis. However, the current thermotherapy devices are often bulky and lack real-time temperature feedback and self-adjustment functions. Here, we developed a multifunctional wearable system for real-time thermotherapy of arthritic joints based on a multilayered flexible electronic device consisting of homomorphic hollow thin-film sensors and heater. The kirigami-serpentine thin-film sensors provide stretchability and rapid response to changes in environmental temperature and humidity, and the homomorphic design offers easy de-coupling of dual-modal sensing signals. Based on a closed-loop control, the thin-film Joule heater exhibits rapid and stable temperature regulation capability, with thermal response time < 1 s and maximum deviation < 0.4 °C at 45 °C. Based on the multifunctional wearable system, we developed a series of user-friendly gears and demonstrated programmable on-demand thermotherapy, real-time personal thermal management, thermal dehumidification, and relief of the pain via increasing blood perfusion. Our innovation offers a promising solution for arthritis management and has the potential to benefit the well-being of thousands of patients.

Identifiers

PMID40355438
PMCPMC12069628

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.