Evidence map›Paper›PMID 40355248›Full record

SynthesisThe British journal of general practice : the journal of the Royal College of General Practitioners2025

Patient and family engagement interventions in primary care patient safety: systematic review and meta-analysis of randomised controlled trials.

Yan Pang, Anna Szücs, Ignacio Ricci-Cabello, Jaheeda Gangannagaripalli, Lay Hoon Goh, Foon Leng Leong, Li Fan Zhou, Jose Maria Valderas

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in The British journal of general practice : the journal of the Royal College of General Practitioners, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yan Pang *Department of Family Medicine, National University Health System (NUHS), Singapore, Singapore; Alice Lee Centre for Nursing Studies, Yong Loo Lin School of Medicine, National University of Singapore, Kent Ridge, Singapore.ORCID 0000-0002-1811-7034
Anna Szücs *Department of Family Medicine, National University Health System (NUHS), Singapore, Singapore; Division of Family Medicine, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Kent Ridge, Singapore; Faculty of Behavioural and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0001-6356-4178
Ignacio Ricci-CabelloHealth Research Institute of the Balearic Islands (IdISBa), Balearic Islands, Spain; Balearic Islands Cochrane Affiliated Centre, Palma, Spain; CIBER de Epidemiología y Salud Pública (CIBERESP), Institute of Health Carlos III, Madrid, Spain.ORCID 0000-0002-4725-8274
Jaheeda GangannagaripalliNIHR Applied Research Collaboration Greater Manchester (ARC-GM), Manchester, UK; Healthy Ageing Research Group, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK; Manchester Academic Health Science Centre, Manchester, UK.ORCID 0000-0003-1375-9406
Lay Hoon GohDepartment of Family Medicine, National University Health System (NUHS), Singapore, Singapore; Division of Family Medicine, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Kent Ridge, Singapore; National University Polyclinics (NUP), Singapore, Singapore.ORCID 0000-0003-1536-3050
Foon Leng LeongDepartment of Family Medicine, National University Health System (NUHS), Singapore, Singapore; Division of Family Medicine, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Kent Ridge, Singapore fl.leong@nus.edu.sg.ORCID 0009-0003-4812-6067
Li Fan ZhouDepartment of Statistics & Data Science, National University of Singapore, Kent Ridge, Singapore.ORCID 0000-0001-6885-6954
Jose Maria ValderasDepartment of Family Medicine, National University Health System (NUHS), Singapore, Singapore; Division of Family Medicine, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Kent Ridge, Singapore; Centre for Research in Health Systems Performance (CRiHSP), National University of Singapore, Singapore, Singapore.ORCID 0000-0002-9299-1555

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEngaging patients and families has been promoted as a key strategy for improving patient safety of health systems. However, evidence remains scarce on the effectiveness of this approach in primary care.

aimTo assess the combined effectiveness of primary care interventions in randomised controlled trials (RCTs) promoting patient and family engagement in patient safety. DESIGN AND

settingA systematic review and meta-analysis.

methodThe review followed PRISMA and Cochrane guidelines. Five electronic databases (Medline, CINAHL, Embase, Web of Science, CENTRAL) were searched from inception to 18 September 2024 with keywords in four blocks (patient and family engagement; patient safety; primary care; randomised controlled trial). Patient and family engagement levels were appraised. Where appropriate, results were combined into meta-analyses.

resultsOf the 19 included records, 12 reported on completed RCTs. Only one intervention integrated patients/families into overall care safety (high engagement); six aimed at enhancing skills and tools (intermediate), and 12 informed patients/families how to engage and prompted them to do it (low). RCTs primarily targeted medication safety, with meta-analyses showing no significant effects on reducing adverse drug events (odds ratio [OR] 0.86, 95% confidence interval [CI] = 0.70 to 1.08) or improving medication appropriateness measured categorically (OR 0.92, 95% CI = 0.76 to 1.13) or continuously (mean difference 0.71, 95% CI = -0.10 to 1.52). Overall risk of bias was low and certainty of evidence very low to moderate.

conclusionExisting randomised controlled evidence on patient and family engagement in primary care remains inconclusive and limited in scope. Future interventions should include higher levels of engagement and address more diverse patient safety outcomes relevant for primary care.

Indexed as

FamilyPatient ParticipationPatient SafetyPrimary Health CareHumansRandomized Controlled Trials as Topicfamily engagementfamily involvementfamily medicinepatient engagementpatient involvementpatient participationpatient safetyprimary health carerandomised controlled trial

Identifiers

PMID40355248
PMCPMC12364509

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.