Evidence map›Paper›PMID 40355020›Full record

ArticleThe Annals of thoracic surgery2025

Association Between Left Ventricular Assist Device Infections and Number of Shared Patients Among Care Providers: A Network Analysis.

Robert B Hawkins, James W Stewart, K Dennie Kim, Hechuan Hou, Michael J Pienta, Russell Funk, Thomas M Cascino, Keith D Aaronson, Preeti N Malani, Lourdes Cabrera and 3 more

Abstract readMulticenter Study
In one paragraph

Article in The Annals of thoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Robert B HawkinsDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan.
James W StewartDepartment of Surgery, University of Michigan, Ann Arbor, Michigan; Department of Surgery, Yale School of Medicine, New Haven, Connecticut.
K Dennie KimDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan; Strategy, Ethics, and Entrepreneurship, Darden School of Business, University of Virginia, Charlottesville, Virginia.
Hechuan HouDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan.
Michael J PientaDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan.
Russell FunkDepartment of Strategic Management and Entrepreneurship, Carlson School of Management, University of Minnesota, Minneapolis, Minnesota.
Thomas M CascinoDivision of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan.
Keith D AaronsonDivision of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan.
Preeti N MalaniDivision of Infectious Diseases, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
Lourdes CabreraDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan.
Francis D PaganiDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan.
Donald S LikoskyDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan. Electronic address: likosky@med.umich.edu.
Michigan Congestive Heart Failure Investigators

Funding

AHRQ HHS R01 HS026003NHLBI NIH HHS HHSN268201100025C
6 · The paper itself

Abstract

backgroundFor patients on durable left ventricular assist devices, prior work has documented that more shared patients among clinicians (connectedness) is associated with improved long-term outcomes. This study examines the association between preadmission clinician connectedness, patient acuity, and postimplant outcomes including infections.

methodsThe Society of Thoracic Surgeons Intermacs National Database was linked to Medicare claims to identify patients undergoing durable left ventricular assist device implantation between 2009 and 2017. Patients were stratified by terciles (low, moderate, high) of provider connectedness. The association between provider connectedness and major infections within 180 days of implant was evaluated by regression analysis, with an interaction term to assess effect modification by patient acuity via Intermacs Patient Profile.

resultsOf the 4985 patients across 127 hospitals, those within networks of low vs high provider connectedness were more commonly Intermacs Profile 1 (12.6% vs 6.7%, P < .001), and designated for destination therapy (3.4% vs 0.7%, P = .002). Patients cared for in centers with high connectedness had a lower risk of infection (β = -0.100, P < .026) and fewer total infections (β = -0.215, P = .014). The risk of infection was most pronounced in higher acuity Intermacs Profile 1 patients (P = .006).

conclusionsPatients in networks with lower clinician connectedness (fewer shared patients) presented with higher acuity. After adjusting for preimplantation risk, lower clinician connectedness was associated with an increased risk of major infections, particularly among high-acuity patients. Measuring and improving network connectedness may be an important quality metric for timely access to advanced heart failure treatment and reducing complications.

Indexed as

Heart-Assist DevicesHeart FailureProsthesis-Related InfectionsAgedFemaleHumansMaleMedicareMiddle AgedRetrospective StudiesUnited States

Identifiers

PMID40355020
PMCPMC13348214

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