Evidence map›Paper›PMID 40354977›Full record

ArticleJournal of pediatric surgery2025

Voice and Swallowing Dysfunction Associated With Extracorporeal Membrane Oxygenation in Pediatric Patients.

Ezer H Benaim, Elizabeth N Ritter, Kelly D Kamp, Christina Dorismond, Lauren K Leeper

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In one paragraph

Article in Journal of pediatric surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ezer H BenaimDepartment of Otolaryngology - Head and Neck Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: ezer.benaim@unchealth.unc.edu.
Elizabeth N RitterDepartment of Otolaryngology - Head and Neck Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Kelly D KampOtolaryngology - Head and Neck Surgery, WakeMed Physician Practices, Raleigh, NC, USA.
Christina DorismondDepartment of Otolaryngology - Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Lauren K LeeperDepartment of Otolaryngology - Head and Neck Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Funding

Research Training in OtolaryngologyT32DC005360 · NIDCD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MANIS, PAUL B · 2003 to 2023
$2.8M
NIDCD NIH HHS T32 DC005360
6 · The paper itself

Abstract

objectivesThis study aims to determine the incidence of vocal fold motion impairment (VFMI) and swallowing dysfunction in pediatric patients undergoing cervical extracorporeal membrane oxygenation (ECMO) and the role of screening for compromise.

methodsA retrospective cohort analysis of voice, swallowing, and respiratory difficulty was performed among pediatric patients undergoing cervical ECMO cannulation and decannulation from 2012 to 2019. Data collected included weight, age, length of hospital stay, duration of intubation, ECMO procedure details, feeding interventions, and swallowing and airway evaluations.

resultsThis study included 77 patients with a median age of 3 days. Right vocal cord hypomobility or immobility was identified in 23 % of patients (n = 18), and 26 % (n = 20) had swallowing dysfunction. Twelve (15.6 %) patients had concurrent VFMI and swallowing dysfunction following decannulation. Median weight at cannulation was significantly lower in patients with VFMI (3.15 kg) than those without (3.93 kg). No significant differences were detected when comparing age, gestational age, type and location of ECMO procedure, and intubation duration/attempts. Despite concern for dysphonia in 42 patients, only 26 underwent flexible fiberoptic laryngoscopy.

conclusionVFMI and swallowing dysfunction are common in pediatric ECMO patients. This study is the first to document a clinically significant risk of vocal and swallowing dysfunction in children requiring ECMO. The study may underestimate the incidence of VFMI and swallowing dysfunction in these patients. In the future, we aim to prospectively evaluate patients after successful ECMO decannulation and extubation to identify VFMI and dysphagia promptly and provide appropriate follow-up and intervention for patients with persistent or prolonged respiratory and feeding difficulty.

Indexed as

Deglutition DisordersExtracorporeal Membrane OxygenationVocal Cord ParalysisVoice DisordersChildChild, PreschoolFemaleHumansIncidenceInfantInfant, NewbornMaleRetrospective StudiesDysphagiaDysphoniaVocal cord paralysisVocal fold hypomobilityVocal fold immobilityVocal fold motion impairment

Identifiers

PMID40354977
PMCPMC12350069

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.