Evidence map›Paper›PMID 40354958›Full record

ArticleThe American journal of cardiology2025

Outcomes of Percutaneous Coronary Interventions Following Transcatheter Aortic Valve Replacement: Insights From the CathPCI Registry.

Christina Lalani, Ravi K Sharma, Jonathan Sevilla-Cazes, Kevin Kennedy, Neel M Butala, Eric A Secemsky, Duane Pinto, Marie-France Poulin, Roger Laham, Dhaval Kolte and 2 more

Abstract read
In one paragraph

Article in The American journal of cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Christina LalaniDivision of Cardiology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Ravi K SharmaDivision of Cardiology, University of Louisville School of Medicine, Louisville, Kentucky; Norton Healthcare, Louisville, Kentucky.
Jonathan Sevilla-CazesDivision of Cardiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Kevin KennedySt Luke's Hospital, Kansas City, Missouri.
Neel M ButalaDivision of Cardiology, Rocky Mountain Regional VA Medical Center, University of Colorado School of Medicine, Aurora, Colorado.
Eric A SecemskyDivision of Cardiology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts; Harvard Medical School, Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Duane PintoDivision of Cardiology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Marie-France PoulinDivision of Cardiology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Roger LahamDivision of Cardiology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Dhaval KolteHarvard Medical School, Richard A. and Susan F. Smith Center for Outcomes Research in Cardiology, Beth Israel Deaconess Medical Center, Boston, Massachusetts; Cardiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
David J CohenDivision of Cardiology, St. Francis Hospital, Roslyn, New York; Cardiovascular Research Foundation, New York, New York.
Robert W YehDivision of Cardiology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts; Division of Cardiology, Rocky Mountain Regional VA Medical Center, University of Colorado School of Medicine, Aurora, Colorado. Electronic address: ryeh@bidmc.harvard.edu.

Funding

Training Program in Cardiovascular ResearchT32HL160522 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI Jennifer E Ho · 2022 to 2026
$2.7M
NHLBI NIH HHS T32 HL160522
6 · The paper itself

Abstract

Although transcatheter aortic valve replacement (TAVR) devices can impair coronary access, there are limited real-world data comparing outcomes of percutaneous coronary intervention (PCI) in post-TAVR versus non-TAVR patients. In this study, we compare procedural characteristics and outcomes between patients with versus without a history of TAVR who undergo PCI. We used claims data for the Medicare population to evaluate the incidence of PCI after TAVR between 2011 and 2017. Then, using the CathPCI Registry, we compared PCI outcomes between patients with a history of TAVR versus propensity score-matched non-TAVR patients. Of the 52,780 Medicare patients who underwent TAVR between 2011 and 2017, the incidence of acute myocardial infarction (AMI) was 10.2% and of PCI was 5.1% at 5 years. At 5 years, the incidence of stroke was 5.0% and of death was 64.0%. In the CathPCI Registry, procedural success for PCI was similar between 1,309 post-TAVR patients versus 5,236 propensity-score matched patients without prior TAVR. However, post-TAVR patients required greater fluoroscopic time (21.9 vs 17.7 minutes, p <0.001) and had higher rates of post-procedural stroke (0.8% vs 0.4%, p = 0.02) and bleeding (5.1% vs 2.9%, p <0.001). Post-TAVR patients were more likely to have repeat PCI in the 3 years post-PCI (HR: 1.36, 95% C.I: 1.09, 1.70) and had higher rates of stroke (HR: 1.65, C.I.: 1.07 to 2.56, p = 0.023) and death (HR: 1.23, C.I.: 1.11-1.38, p <0.001) compared to non-TAVR patients. In conclusion, in the CathPCI Registry, patients with a history of TAVR appeared to have similar procedural success but longer fluoroscopic times, more frequent post-procedural bleeding and stroke, and a higher likelihood of a repeat PCI compared with matched patients without a history of TAVR.

Indexed as

Aortic Valve StenosisMyocardial InfarctionPercutaneous Coronary InterventionPostoperative ComplicationsRegistriesTranscatheter Aortic Valve ReplacementAgedAged, 80 and overFemaleHumansIncidenceMalePropensity ScoreStrokeTreatment OutcomeUnited StatesCathPCI RegistryPost-TAVR PCI

Identifiers

PMID40354958
PMCPMC13107208

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.