Evidence map›Paper›PMID 40354593›Full record

ArticleJCO oncology practice2026

High-Deductible Health Plans and Out-of-Pocket Health Care Costs Among Younger Patients With Multiple Myeloma.

Mark Aaron Fiala, Mengmeng Ji, Michael Slade, John H Huber, Yi-Hsuan Shih, Mei Wang, Graham A Colditz, Shi-Yi Wang, Ravi Vij, Su-Hsin Chang

Abstract read
In one paragraph

Article in JCO oncology practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mark Aaron FialaDivision of Oncology, Washington University School of Medicine, St Louis, MO.ORCID 0000-0002-0208-5023
Mengmeng JiDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St Louis, MO.ORCID 0000-0002-1205-0369
Michael SladeDivision of Oncology, Washington University School of Medicine, St Louis, MO.
John H HuberDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St Louis, MO.
Yi-Hsuan ShihDepartment of Electrical and Systems Engineering, Washington University in St Louis, St Louis, MO.ORCID 0000-0003-2029-8230
Mei WangDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St Louis, MO.ORCID 0000-0002-3560-9460
Graham A ColditzDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St Louis, MO.ORCID 0000-0002-7307-0291
Shi-Yi WangDepartment of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT.ORCID 0000-0002-3294-5784
Ravi VijDivision of Oncology, Washington University School of Medicine, St Louis, MO.ORCID 0000-0001-8795-3610
Su-Hsin ChangDivision of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St Louis, MO.ORCID 0000-0001-5872-9556

Funding

WU INSTITUTE OF CLINICAL AND TRANSLATIONAL SCIENCESUL1TR002345 · NCATS · WASHINGTON UNIVERSITY · PI William G. Powderly · 2017 to 2026
$97.8M
Comparative modeling of multiple myeloma across myeloma control continuuum: prevention, treatment, and disparity reductionU01CA265735 · NCI · WASHINGTON UNIVERSITY · PI CHANG, SU-HSIN, WANG, SHIYI · 2021 to 2025
$3.2M
Addressing racial disparities in monoclonal gammopathy of undetermined significance and progression to multiple myeloma from a prevention perspectiveR01CA253475 · NCI · WASHINGTON UNIVERSITY · PI CHANG, SU-HSIN · 2020 to 2022
$1.1M
NCATS NIH HHS UL1 TR002345NCI NIH HHS R01 CA253475NCI NIH HHS U01 CA265735
6 · The paper itself

Abstract

purposeThis study aimed to determine if high-deductible health plan (HDHP) enrollment contributes to financial burden and hinders access to care for patients with multiple myeloma (MM). MATERIALS AND

methodsPatients diagnosed with MM from 2010 to 2020 were identified in Merative MarketScan, an employer-based health insurance database. Primary outcomes were total health care and out-of-pocket (OOP) costs in the year after diagnosis. Secondary outcomes included time to treatment initiation and stem-cell transplant receipt. Multivariable analyses using linear, logistic, and Cox regression were performed, as appropriate. Covariates included age, sex, year diagnosed, comorbidities, data provider, and stem-cell transplant receipt.

resultsThe cohort included 4,029 patients; 17.6% were enrolled on HDHPs. HDHP enrollees were younger (mean age, 54.9

conclusionCompared with standard plan enrollees, OOP costs were higher for HDHP enrollees in the year after diagnosis, but HDHP enrollment was not associated with delays in treatment initiation or reduced access to stem-cell transplant.

Indexed as

Deductibles and CoinsuranceHealth Care CostsHealth ExpendituresMultiple MyelomaAdultAgedFemaleHumansMaleMiddle Aged

Identifiers

PMID40354593
PMCPMC12354019

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.