Evidence map›Paper›PMID 40354572›Full record

Trial reportEnvironmental health perspectives2025

Effects of Cooking with Liquefied Petroleum Gas or Biomass Fuels on Neurodevelopmental Outcomes in Preschool-Age Children Living in Puno, Peru.

Carolyn J Reuland, Laura Nicolaou, Maureen M Black, Mingling Yang, Ryan McCord, Milagros Alvarado, Fiorela Arana, Paola S Sanchez, Kendra N Williams, Shakir Hossen and 3 more

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Environmental health perspectives, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Carolyn J ReulandDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Laura NicolaouDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Maureen M BlackDepartment of Pediatrics, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Mingling YangDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Ryan McCordSanford School of Public Policy, Duke University, Durham, North Carolina, USA.
Milagros AlvaradoLatin American Center of Excellence on Climate Change and Health, Universidad Peruana Cayetano Heredia, Lima, Peru.
Fiorela AranaLatin American Center of Excellence on Climate Change and Health, Universidad Peruana Cayetano Heredia, Lima, Peru.
Paola S SanchezLatin American Center of Excellence on Climate Change and Health, Universidad Peruana Cayetano Heredia, Lima, Peru.
Kendra N WilliamsCenter for Global Non-Communicable Disease Research and Training, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Shakir HossenDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Marilú ChiangBiomedical Research Unit, A.B. PRISMA, Lima, Peru.
Stella M HartingerLatin American Center of Excellence on Climate Change and Health, Universidad Peruana Cayetano Heredia, Lima, Peru.
William CheckleyDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.ORCID 0000-0003-1106-8812

Funding

Household Air Pollution and Health: A Multi-Country LPG Intervention TrialUM1HL134590 · NHLBI · EMORY UNIVERSITY · PI CHECKLEY, WILLIAM, CLASEN, THOMAS F · 2016 to 2021
$31.1M
UJMT – ORWH – Gazzetta, Issa-BoubeD43TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI William Checkley, Benjamin H. Chi · 2017 to 2026
$14.8M
Research training in chronic, non-communicable respiratory diseases in PeruD43TW011502 · FIC · JOHNS HOPKINS UNIVERSITY · PI CHECKLEY, WILLIAM, HARTINGER, STELLA MARIA · 2019 to 2023
$1.2M
FIC NIH HHS D43 TW009340FIC NIH HHS D43 TW011502NHLBI NIH HHS UM1 HL134590
6 · The paper itself

Abstract

backgroundBurning biomass fuels for cooking is a widespread environmental exposure that may adversely affect child health. We conducted an 18-month randomized field trial comparing a liquefied petroleum gas (LPG) stove, continuous fuel delivery, and behavioral messaging intervention starting in pregnancy through infancy with usual cooking practices using biomass fuels in Puno, Peru. A total of 800 pregnant women were enrolled. The intervention successfully lowered personal exposures to fine particulate matter with aerodynamic diameter

objectiveWe sought to evaluate the effects of the intervention on neurodevelopment among preschool-age offspring.

methodsWe conducted a longitudinal follow-up study in a subset of Peruvian children born during the trial and assessed neurodevelopment between 24 and 36 months of age. Trained staff measured neurodevelopment using the Bayley Scales of Infant and Toddler Development Third Edition (Bayley-III). The Bayley-III neurodevelopmental assessment test yields separate cognition, language, and motor scores. We measured personal exposures to

resultsA total of 301 children (mean age DISCUSSION: The LPG intervention did not improve neurodevelopment in Peruvian children. We also did not find an association between prenatal or postnatal

Indexed as

Air PollutantsAir Pollution, IndoorChild DevelopmentCookingEnvironmental ExposurePetroleumBiomassChild, PreschoolFemaleHumansInfantIntention to Treat AnalysisLongitudinal StudiesMaleParticulate MatterPeruAir PollutantsParticulate MatterPetroleum

Identifiers

PMID40354572
PMCPMC12142655

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.