Evidence map›Paper›PMID 40354562›Full record

ArticleAge and ageing2025

Validation of the standard assessment of global everyday activities (SAGEA) scale for dementia diagnosis.

Jolene Phelps, Dylan X Guan, Koon Teo, Martin O'Donnell, Salim Yusuf, Jackie Bosch, Zahinoor Ismail, Eric E Smith

Abstract readValidation Study
In one paragraph

Article in Age and ageing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Cognitive reserve and everyday functioning in cognitively unimpaired older adults: evidence from the CAN-PROTECT study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jolene PhelpsDepartment of Mechanical Engineering and Division of Medical Sciences, University of Victoria, Victoria, British Columbia, Canada.
Dylan X GuanHotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada.
Koon TeoDepartment of Medicine, Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.
Martin O'DonnellCollege of Medicine, Nursing and Health Sciences, University of Galway, Galway, Ireland.
Salim YusufDepartment of Medicine, Population Health Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada.
Jackie BoschFaculty of Health Sciences, Population Health Research Institute, Hamilton, Ontario, Canada.
Zahinoor IsmailDepartments of Psychiatry, Clinical Neurosciences and Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Eric E SmithDepartment of Clinical Sciences and Radiology, Hotchkiss Brain Institute, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStandardised questionnaires of cognitive symptoms and cognitive-related function can assist in diagnosing dementia. The Standardised Assessment of Global Everyday Activities (SAGEA) is a 15-item questionnaire, developed to measure functional status by capturing cognitive symptoms, basic and instrumental activities of daily living, participation in activites, and mobility.

objectiveThe aim of this study was to validate the SAGEA as a tool for assessing cognitive dysfunction in dementia.

methodsParticipants with dementia, mild cognitive impairment (MCI) or subjective cognitive decline (SCD) were selected from the clinic-based Prospective Registry for Persons with Memory Symptoms (PROMPT), and cognitively asymptomatic, unimpaired controls were selected from the Canadian Platform for Research Online to Investigate Health, Quality of Life, Cognition, Behaviour, Function and Caregiving in Ageing study.

resultsSAGEA scores correlated well with the Lawton-Brody scale for instrumental activities of daily living (r = -0.68, P < 0.0001). SAGEA scores differed significantly across participant groups, highest for individuals with dementia (17.7 ± 8.59) followed by MCI (10.8 ± 9.10), SCD (8.07 ± 7.06) and controls (1.60 ± 2.07). The SAGEA classified dementia with an AUC of 0.97, sensitivity of 94.5% and specificity of 94.6% at a cut-off point of ≥6 points based on Youden's index. A dementia diagnosis algorithm based on the SAGEA distinguished dementia from controls with a sensitivity of 68% and specificity of 100%.

conclusionsThis study supports the utility of the SAGEA as an adjunct to diagnosing dementia and a potentially useful screening tool.

Indexed as

Activities of Daily LivingCognitionCognitive DysfunctionDementiaGeriatric AssessmentAgedAged, 80 and overCanadaCase-Control StudiesFemaleHumansMaleMiddle AgedNeuropsychological TestsPredictive Value of TestsProspective Studiesactivities of daily livingdementiadiagnosisolder peoplestandardised assessment of global everyday activities

Identifiers

PMID40354562
PMCPMC12068478

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.