Evidence map›Paper›PMID 40354522›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

A mechanism for MEX-5-driven disassembly of PGL-3/RNA condensates in vitro.

Natasha S Lewis, Silja Zedlitz, Hannes Ausserwöger, Patrick M McCall, Lars Hubatsch, Marco Nousch, Martine Ruer-Gruß, Carsten Hoege, Frank Jülicher, Christian R Eckmann and 2 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. A mechanism for MEX-5-driven disassembly of PGL-3/RNA condensates in vitro.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Natasha S LewisMax Planck Institute of Molecular Cell Biology and Genetics, Dresden 01307, Germany.ORCID 0009-0006-9309-1360
Silja ZedlitzMax Planck Institute of Molecular Cell Biology and Genetics, Dresden 01307, Germany.ORCID 0000-0002-7584-2099
Hannes AusserwögerCentre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom.
Patrick M McCallMax Planck Institute of Molecular Cell Biology and Genetics, Dresden 01307, Germany.ORCID 0000-0002-6623-4673
Lars HubatschMax Planck Institute of Molecular Cell Biology and Genetics, Dresden 01307, Germany.
Marco NouschInstitute of Biology, Martin Luther University Halle-Wittenberg, Halle, Saale 06120, Germany.
Martine Ruer-GrußMax Planck Institute of Molecular Cell Biology and Genetics, Dresden 01307, Germany.ORCID 0000-0003-0984-4130
Carsten HoegeMax Planck Institute of Molecular Cell Biology and Genetics, Dresden 01307, Germany.
Frank JülicherMax Planck Institute for the Physics of Complex Systems, Dresden 01187, Germany.ORCID 0000-0003-4731-9185
Christian R EckmannInstitute of Biology, Martin Luther University Halle-Wittenberg, Halle, Saale 06120, Germany.ORCID 0000-0002-1112-4936
Tuomas P J KnowlesCentre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, United Kingdom.ORCID 0000-0002-7879-0140
Anthony A HymanMax Planck Institute of Molecular Cell Biology and Genetics, Dresden 01307, Germany.ORCID 0000-0003-0851-704X

Funding

Deutsche Forschungsgemeinschaft (DFG) EXC-2068- 390729961EC | European Research Council (ERC) ID 101001615
6 · The paper itself

Abstract

MEX-5 regulates the formation and dissolution of P granules in

Indexed as

Biomolecular CondensatesCaenorhabditis elegansCaenorhabditis elegans ProteinsRNARNA-Binding ProteinsRNA, HelminthAnimalsThermodynamicsCaenorhabditis elegans ProteinsMEX-5 protein, C elegansRNARNA-Binding ProteinsRNA, HelminthC. elegansphase-separationpolarity

Identifiers

PMID40354522
PMCPMC12107180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.