Evidence map›Paper›PMID 40354478›Full record

ArticlePloS one2025

Insomnia symptoms among individuals with osteoarthritis and symptoms indicative of osteoarthritis: A population-based cross-sectional study using the CLSA.

Melissa Cavallo, Elizabeth M Badley, Anthony V Perruccio

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Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Melissa CavalloArthritis Community Research and Epidemiology Unit and Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0001-8652-5913
Elizabeth M BadleyArthritis Community Research and Epidemiology Unit and Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.
Anthony V PerruccioArthritis Community Research and Epidemiology Unit and Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.ORCID https://orcid.org/0000-0002-4389-0993

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the prevalence and examine the likelihood of insomnia symptoms in middle- and older-aged adults with an osteoarthritis (OA) diagnosis and with joint symptoms indicative of OA but without a diagnosis, in a population-based sample.

methodsData are from the Canadian Longitudinal Study on Aging (participants aged >45). Individuals reported on doctor-diagnosed OA (hand, hip, or knee) and joint symptoms typical of OA, irrespective of OA diagnosis. A three-level 'OA-status' variable was derived: diagnosed OA; joint symptoms-no OA; no symptoms-no OA (controls). Participants responded to sleep-related questions and were categorized as experiencing insomnia symptoms (yes/no). Logistic regression analysis examined the association between insomnia symptoms and OA status, adjusting for a number of covariates.

resultsOf 21,422 respondents, OA was reported by 29.1% (mean age 68.2) and 17.2% reported joint symptoms-no OA (mean age 63.9). One third of those with diagnosed OA and with joint symptoms-no OA reported insomnia symptoms compared to a quarter of controls. Those with OA and with joint symptoms-no OA were similarly more likely to report insomnia symptoms than controls (odds ratio (OR) 1.25, 95% CI 1.17-1.35 and OR 1.32, 95% CI 1.21-1.43). Also significantly associated with insomnia symptoms were female sex, current smoker, lower activity level, multiple chronic conditions and depressive symptoms. Odds ratio magnitudes were greatest for depressive symptoms (OR 2.50, 95% CI 2.26-2.76), comorbidity count (3 + vs. 0 OR 1.68, 95% CI 1.47-1.91) and female sex (OR 1.46, 95% 1.37-1.55).

conclusionInsomnia symptoms were not uncommon among comparatively younger individuals with typical OA joint symptoms and those with OA. This suggests that healthcare providers should address sleep-related issues in those consulting for joint pain, irrespective of diagnosis. Given their high prevalence, this also has implications for sleep-related issues at a population level.

Indexed as

OsteoarthritisSleep Initiation and Maintenance DisordersAgedAged, 80 and overCanadaCross-Sectional StudiesFemaleHumansLongitudinal StudiesMaleMiddle AgedPrevalence

Identifiers

PMID40354478
PMCPMC12068708

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.