Evidence map›Paper›PMID 40354398›Full record

ArticlePloS one2025

Effectiveness of a clinical decision support system with prediction modeling to identify patients with health-related social needs in the emergency department: Study protocol.

Olena Mazurenko, Christopher A Harle, Justin Blackburn, Nir Menachemi, Adam Hirsh, Shaun Grannis, Malaz Boustani, Paul I Musey, Titus K Schleyer, Lindsey M Sanner and 1 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06655974 (Protocol for Evaluating the Effectiveness of a Clinical Decision Support System With Prediction Modeling to Identify Patients With Health-related Social Needs in the Emergency Department), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06655974 nacompletednot on this map

Protocol for Evaluating the Effectiveness of a Clinical Decision Support System With Prediction Modeling to Identify Patients With Health-related Social Needs in the Emergency Department

TypeinterventionalSponsorIndiana UniversityRan2025 to 2025Enrolled518,512ConditionsEmergency Service, Hospital, Social Determinants of HealthArmsHealth-related social needs decision support system
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Olena MazurenkoDepartment of Health Policy & Management, Richard M. Fairbanks School of Public Health, Indiana University Indianapolis, Indianapolis, Indiana, United States of America.ORCID https://orcid.org/0000-0002-1003-9262
Christopher A HarleDepartment of Health Policy & Management, Richard M. Fairbanks School of Public Health, Indiana University Indianapolis, Indianapolis, Indiana, United States of America.
Justin BlackburnDepartment of Health Policy & Management, Richard M. Fairbanks School of Public Health, Indiana University Indianapolis, Indianapolis, Indiana, United States of America.ORCID https://orcid.org/0000-0002-1811-2081
Nir MenachemiDepartment of Health Policy & Management, Richard M. Fairbanks School of Public Health, Indiana University Indianapolis, Indianapolis, Indiana, United States of America.
Adam HirshDepartment of Psychology, School of Science, Indiana University Indianapolis, Indianapolis, Indiana, United States of America.
Shaun GrannisRegenstrief Institute, Indianapolis, Indiana, United States of America.
Malaz BoustaniCenter for Health Innovation and Implementation Science, School of Medicine, Indiana University, Indianapolis, Indiana, United States of America.
Paul I MuseyDepartment of Emergency Medicine, School of Medicine, Indiana University, Indianapolis, Indiana, United States of America.
Titus K SchleyerRegenstrief Institute, Indianapolis, Indiana, United States of America.ORCID https://orcid.org/0000-0003-1829-971X
Lindsey M SannerDepartment of Health Policy & Management, Richard M. Fairbanks School of Public Health, Indiana University Indianapolis, Indianapolis, Indiana, United States of America.
Joshua R VestDepartment of Health Policy & Management, Richard M. Fairbanks School of Public Health, Indiana University Indianapolis, Indianapolis, Indiana, United States of America.

Funding

Quality Assurance and Quality Control Project Management: Improving Submissions and Study Conduct in the Human Subjects Research Prior Approval ProcessUL1TR002529 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M, WIEHE, SARAH ELIZABETH · 2018 to 2022
$27.2M
AHRQ HHS R01 HS028008NCATS NIH HHS UL1 TR002529
6 · The paper itself

Abstract

introductionHealth-related social needs (HRSNs) encompass various non-medical risks from a patient's life circumstances. The emergency department (ED) is a crucial yet challenging setting for addressing patient HRSNs, a clinical decision support (CDS) intervention could assist in identifying patients at high risk of having HRSNs. This project aims to implement and evaluate a CDS intervention that offers ED clinicians risk prediction scores to determine which patients will likely screen positive for one or more HRSNs. MATERIALS &

methodsThe FHIR-based CDS intervention, implemented in the ED setting of a health system in Indianapolis, Indiana, will use health information exchange data to generate logit-derived probability scores that estimate an adult patient's likelihood of screening positive for each of the following HRSNs: housing instability, food insecurity, transportation barriers, financial strain, and history of legal involvement. For each HRSN, ED clinicians will have access to the patient's likelihood of screening positive categorized as "high," "medium," or "low" based on tertiles in the distribution of each likelihood score. Clinician participation in the CDS will be voluntary. The intervention's effects will be assessed using a difference-in-difference approach with a pre-post design and a propensity-matched comparison group of ED patients from the same metropolitan area. Outcomes of interest include whether a formal HRSN screening was conducted, whether a referral was made to an HRSN service provider (e.g., social worker), and whether a repeat ED revisit (at 3, 7, and 30 days) or primary care follow-up (within 7 days) occurred. DISCUSSION: Efficiently and accurately identifying patients with HRSNs could help link them to needed services, improving outcomes and reducing healthcare costs. This protocol will contribute to a growing body of research on the role of CDS interventions in facilitating improved screenings and referrals for HRSNs.

trial registrationClincialtrials.gov NCT06655974.

Indexed as

Decision Support Systems, ClinicalEmergency Service, HospitalAdultFemaleHumansIndianaMale

Identifiers

PMID40354398
PMCPMC12068607

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.